Literature DB >> 22303506

Effect of 10% phenylephrine eye drops on systemic blood pressure in normotensive & hypertensive patient.

Jagdish Bhatia1, Mathew Varghese, Arti Bhatia.   

Abstract

OBJECTIVES: A prospective study to evaluate the effect of 10% Phenylephrine eye drops on systemic blood pressure in normotensive and hypertensive patients.
METHODS: The sample comprised of 55 normotensive patients and 34 hypertensive patients were subjected to 10% Phenylephrine eye drops during routine eye examination.
RESULTS: No statistically and clinically significant increase in blood pressure after the instillation of 10% Phenylephrine eye drops was seen in 87% of normotensive patients and 76% of hypertensive patients. Mild rise of blood pressure was seen in 11% of normotensive patients and in 15% of the hypertensive patients. Only one patient (3%) had severe rise of blood pressure in the hypertensive group.
CONCLUSION: This study shows that pupillary dilatation with 10% Phenylephrine eye drops did not significantly increase systemic blood pressure in normotensive and hypertensive patients. Although precautions should be taken when used in hypertensive patients.

Entities:  

Year:  2009        PMID: 22303506      PMCID: PMC3269617          DOI: 10.5001/omj.2009.8

Source DB:  PubMed          Journal:  Oman Med J        ISSN: 1999-768X


  8 in total

1.  Comparison of the cardiovascular effects of 2.5% phenylephrine and 10% phenylephrine during ophthalmic surgery.

Authors:  R Malhotra; G Banerjee; W Brampton; N C Price
Journal:  Eye (Lond)       Date:  1998       Impact factor: 3.775

2.  Systemic effects of topical phenylephrine.

Authors:  S Samantary; A Thomas
Journal:  Indian J Ophthalmol       Date:  1975-04       Impact factor: 1.848

3.  Hazards of the use of sympathomimetic drugs in ophthalmology.

Authors:  W H HAVENER; J W HENDERSON; W U MCREYNOLDS
Journal:  AMA Arch Ophthalmol       Date:  1956-08

4.  A comparative study of the efficacy of 2.5% phenylephrine and 10% phenylephrine in pre-operative mydriasis for routine cataract surgery.

Authors:  R C Symons; M J Walland; D V Kaufman
Journal:  Eye (Lond)       Date:  1997       Impact factor: 3.775

5.  Acute systemic hypertension after conjunctival instillation of phenylephrine hydrochloride.

Authors:  J T Wilensky; H J Woodward
Journal:  Am J Ophthalmol       Date:  1973-07       Impact factor: 5.258

6.  Possible adverse effects from topical ocular 10% phenylephrine.

Authors:  F T Fraunfelder; A F Scafidi
Journal:  Am J Ophthalmol       Date:  1978-04       Impact factor: 5.258

7.  Systemic absorption and cardiovascular effects of phenylephrine eyedrops.

Authors:  V Kumar; R D Schoenwald; D S Chien; A J Packer; W W Choi
Journal:  Am J Ophthalmol       Date:  1985-02-15       Impact factor: 5.258

8.  Phenylephrine eye drops in ophthalmic surgery--a clinical study on cardiovascular effects.

Authors:  K W Chin; N M Law; M K Chin
Journal:  Med J Malaysia       Date:  1994-06
  8 in total

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