OBJECTIVES: To determine the frequency of different HLA-antigens in patients with plaque psoriasis in the Omani Arab population. METHODS: Fifty four Omani patients clinically diagnosed with plaque psoriasis attending the dermatology outpatient clinic in Al-Nahdah Hospital (the tertiary dermatology centre in Oman) were selected for HLA studies. RESULTS: HLA-B52 was present in 20.4% of patients 11/54 and in 5% of controls without psoriasis 5/100. For the association p was <0.004 and the relative risk (RR) was 4.86. CONCLUSION: Psoriasis does not appear to be associated universally with the same HLA antigens. The association of HLA-B52 with plaque psoriasis in Omani patients compares with the HLA-Cw6, -Bw57 and -DR7 preponderance in most other ethnic groups.
OBJECTIVES: To determine the frequency of different HLA-antigens in patients with plaque psoriasis in the Omani Arab population. METHODS: Fifty four Omani patients clinically diagnosed with plaque psoriasis attending the dermatology outpatient clinic in Al-Nahdah Hospital (the tertiary dermatology centre in Oman) were selected for HLA studies. RESULTS: HLA-B52 was present in 20.4% of patients 11/54 and in 5% of controls without psoriasis 5/100. For the association p was <0.004 and the relative risk (RR) was 4.86. CONCLUSION:Psoriasis does not appear to be associated universally with the same HLA antigens. The association of HLA-B52 with plaque psoriasis in Omani patients compares with the HLA-Cw6, -Bw57 and -DR7 preponderance in most other ethnic groups.
Authors: S S Seki; K Sugimura; M Ota; J Matsuzawa; Y Katsuyama; K Ishizuka; T Mochizuki; K Suzuki; O Yoneyama; N Mizuki; T Honma; H Inoko; H Asakura Journal: Tissue Antigens Date: 2001-08
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Authors: Haider H Zalzala; Galawish A Abdullah; Mohammed Y Abbas; Hyam R Mohammedsalih; Batool M Mahdi Journal: Saudi Med J Date: 2018-09 Impact factor: 1.484