Literature DB >> 22301852

Interference of a new cyclometallated Pt compound with Cu binding to amyloid-β peptide.

Isabelle Sasaki1, Christian Bijani, Sonia Ladeira, Valérie Bourdon, Peter Faller, Christelle Hureau.   

Abstract

Coordination of a cyclometallated Pt(II) complex (1) to an amyloid-β peptide was probed by NMR and ESI-MS. Furthermore, EPR showed that binding of 1 to the Cu(II)-amyloid-β species resulted in a reshuffling of the Cu(II) coordination sphere, which was absent or lower for the sister non cyclometallated Pt(II) complexes.

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Year:  2012        PMID: 22301852     DOI: 10.1039/c2dt12177h

Source DB:  PubMed          Journal:  Dalton Trans        ISSN: 1477-9226            Impact factor:   4.390


  7 in total

1.  Modulation of amyloid-β aggregation by histidine-coordinating Cobalt(III) Schiff base complexes.

Authors:  Marie C Heffern; Pauline T Velasco; Lauren M Matosziuk; Joseph L Coomes; Constantine Karras; Mark A Ratner; William L Klein; Amanda L Eckermann; Thomas J Meade
Journal:  Chembiochem       Date:  2014-06-24       Impact factor: 3.164

2.  Platinum(II) O,S Complexes Inhibit the Aggregation of Amyloid Model Systems.

Authors:  Daniele Florio; Anna Maria Malfitano; Sarah Di Somma; Carolin Mügge; Wolfgang Weigand; Giarita Ferraro; Ilaria Iacobucci; Maria Monti; Giancarlo Morelli; Antonello Merlino; Daniela Marasco
Journal:  Int J Mol Sci       Date:  2019-02-14       Impact factor: 5.923

3.  A catalytic antioxidant for limiting amyloid-beta peptide aggregation and reactive oxygen species generation.

Authors:  Luiza M F Gomes; Atif Mahammed; Kathleen E Prosser; Jason R Smith; Michael A Silverman; Charles J Walsby; Zeev Gross; Tim Storr
Journal:  Chem Sci       Date:  2018-12-03       Impact factor: 9.825

4.  Chemical strategies to modify amyloidogenic peptides using iridium(iii) complexes: coordination and photo-induced oxidation.

Authors:  Juhye Kang; Jung Seung Nam; Hyuck Jin Lee; Geewoo Nam; Hyun-Woo Rhee; Tae-Hyuk Kwon; Mi Hee Lim
Journal:  Chem Sci       Date:  2019-06-05       Impact factor: 9.825

5.  Modification of Aβ Peptide Aggregation via Covalent Binding of a Series of Ru(III) Complexes.

Authors:  Luiza M F Gomes; Janaina C Bataglioli; Allison J Jussila; Jason R Smith; Charles J Walsby; Tim Storr
Journal:  Front Chem       Date:  2019-12-03       Impact factor: 5.221

6.  A Comparative Study of the Effects of Platinum (II) Complexes on β-Amyloid Aggregation: Potential Neurodrug Applications.

Authors:  Sara La Manna; Daniele Florio; Ilaria Iacobucci; Fabiana Napolitano; Ilaria De Benedictis; Anna Maria Malfitano; Maria Monti; Mauro Ravera; Elisabetta Gabano; Daniela Marasco
Journal:  Int J Mol Sci       Date:  2021-03-16       Impact factor: 5.923

7.  Modulation of amyloid-β aggregation by metal complexes with a dual binding mode and their delivery across the blood-brain barrier using focused ultrasound.

Authors:  Tiffany G Chan; Carmen L Ruehl; Sophie V Morse; Michelle Simon; Viktoria Rakers; Helena Watts; Francesco A Aprile; James J Choi; Ramon Vilar
Journal:  Chem Sci       Date:  2021-06-15       Impact factor: 9.825

  7 in total

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