| Literature DB >> 22301166 |
Wei Zhang1, Meng Zhang, Kuangfei Lin, Wenfang Sun, Bang Xiong, Meijin Guo, Xinhong Cui, Rongbing Fu.
Abstract
The acute and chronic toxicological effects of carbamazepine (CBZ) on Scenedesmus obliquus and Chlorella pyrenoidosa were explored for the first time in this study. The results showed that CBZ could significantly inhibit the growth of the two algae in almost all treatment groups. EC(50) values indicated that, CBZ had a relatively limited acute toxic effect (0-144 h) on S. obliquus and C. pyrenoidosa, while, chronic tests (5-30 d) displayed higher toxicity. Chlorophyll a syntheses were nearly all inhibited by CBZ exposure. However, superoxide dismutase (SOD) and catalase (CAT) activities in acute tests of both algae were markedly promoted. According to the results, Chlorophyll a content and CAT activity of S. obliquus were more sensitive to CBZ than that of C. pyrenoidosa. While for SOD, quite to the contrary, C. pyrenoidosa was more vulnerable. We obtained a similar result in chronic tests. This research furthers our understanding of CBZ toxicity to aquatic organisms.Entities:
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Year: 2012 PMID： 22301166 DOI： 10.1016/j.etap.2011.12.024
Source DB: PubMed Journal: Environ Toxicol Pharmacol ISSN： 1382-6689 Impact factor: 4.860