Literature DB >> 2230063

Adverse interactions encountered when using trazodone to treat insomnia associated with fluoxetine.

A Metz1, R I Shader.   

Abstract

The authors report adverse interactions encountered when using low dose (25-75 mg) trazodone to treat insomnia associated with fluoxetine. Sixteen patients had good hypnotic responses to trazodone, but five needed to stop the medication due to excessive sedation. Three cases are described.

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Year:  1990        PMID： 2230063     DOI： 10.1097/00004850-199007000-00004

Source DB:  PubMed          Journal:  Int Clin Psychopharmacol        ISSN： 0268-1315            Impact factor:   1.659


  5 in total

Review 1.  Metabolism of some "second"- and "fourth"-generation antidepressants: iprindole, viloxazine, bupropion, mianserin, maprotiline, trazodone, nefazodone, and venlafaxine.

Authors:  S Rotzinger; M Bourin; Y Akimoto; R T Coutts; G B Baker
Journal:  Cell Mol Neurobiol       Date:  1999-08       Impact factor: 5.046

Review 2.  Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions.

Authors:  R J Bertz; G R Granneman
Journal:  Clin Pharmacokinet       Date:  1997-03       Impact factor: 6.447

Review 3.  Trazodone. A review of its pharmacology, therapeutic use in depression and therapeutic potential in other disorders.

Authors:  M Haria; A Fitton; D McTavish
Journal:  Drugs Aging       Date:  1994-04       Impact factor: 3.923

Review 4.  Comparative tolerability profiles of the newer versus older antidepressants.

Authors:  M V Rudorfer; H K Manji; W Z Potter
Journal:  Drug Saf       Date:  1994-01       Impact factor: 5.606

Review 5.  Sleep disturbances and depression: risk relationships for subsequent depression and therapeutic implications.

Authors:  Peter L Franzen; Daniel J Buysse
Journal:  Dialogues Clin Neurosci       Date:  2008       Impact factor: 5.986
  5 in total

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