PURPOSE: The purpose of this study is to use a novel wireless motility capsule to compare gastric emptying and small bowel transit times in critically ill trauma patients and healthy volunteers. MATERIALS AND METHODS: We evaluated gastric emptying, small bowel transit time, and total intestinal transit time in 8 critically ill trauma patients. These data were compared with those obtained in 87 healthy volunteers from a separate trial. Data were obtained with a motility capsule that wirelessly transmitted pH, pressure, and temperature to a recorder attached to each subject's abdomen. RESULTS: The gastric emptying time was significantly longer in critically ill patients (median, 13.9; interquartile range [IQR], 6.6-48.3 hours) than in healthy volunteers (median, 3.0; IQR, 2.5-3.9 hours), P < .001. The small bowel transit time in critically ill patients was significantly longer than in healthy volunteers (median, 6.7 hours; IQR, 4.4-8.5 hours vs median, 3.8 hours; IQR, 3.1-4.7 hours), P = .01. Furthermore, the capsules passed after 10 (IQR, 8.5-13) days in the critical care group and 1.2 (IQR, 0.9-1.9) days in healthy volunteers (P < .001). CONCLUSIONS: Both gastric emptying and small bowel transit were delayed in critically ill trauma patients.
PURPOSE: The purpose of this study is to use a novel wireless motility capsule to compare gastric emptying and small bowel transit times in critically ill traumapatients and healthy volunteers. MATERIALS AND METHODS: We evaluated gastric emptying, small bowel transit time, and total intestinal transit time in 8 critically ill traumapatients. These data were compared with those obtained in 87 healthy volunteers from a separate trial. Data were obtained with a motility capsule that wirelessly transmitted pH, pressure, and temperature to a recorder attached to each subject's abdomen. RESULTS: The gastric emptying time was significantly longer in critically ill patients (median, 13.9; interquartile range [IQR], 6.6-48.3 hours) than in healthy volunteers (median, 3.0; IQR, 2.5-3.9 hours), P < .001. The small bowel transit time in critically ill patients was significantly longer than in healthy volunteers (median, 6.7 hours; IQR, 4.4-8.5 hours vs median, 3.8 hours; IQR, 3.1-4.7 hours), P = .01. Furthermore, the capsules passed after 10 (IQR, 8.5-13) days in the critical care group and 1.2 (IQR, 0.9-1.9) days in healthy volunteers (P < .001). CONCLUSIONS: Both gastric emptying and small bowel transit were delayed in critically ill traumapatients.
Authors: Kirsten A Turlo; Jason Scapa; Pooneh Bagher; Allan W Jones; Robert Feil; Ronald J Korthuis; Steven S Segal; M Luisa Iruela-Arispe Journal: Arterioscler Thromb Vasc Biol Date: 2013-07-25 Impact factor: 8.311
Authors: Tim O Vilz; Dimitrios Pantelis; Philipp Lingohr; Rolf Fimmers; Anke Esmann; Thomas Randau; Jörg C Kalff; Martin Coenen; Sven Wehner Journal: BMJ Open Date: 2016-07-08 Impact factor: 2.692