Literature DB >> 22298888

Update of the past year: a review from IDSA 2011.

David L McCollum1.   

Abstract

The Infectious Diseases Society of America Annual Meeting serves as a time of expert review of the year's most important innovations. Important new information on HIV infection incidence was discussed. The remarkable efficacy of "treatment as prevention" in the HIV Prevention Trials Network (HPTN) 052 study and the proper place of oral preexposure prophylaxis were among the important prevention topics. Key engagement-in-care research indicates that only 19% of HIV-infected persons in the United States have a plasma HIV RNA level below the limits of assay detection. Among antiretroviral topics, the role of the newly approved nonnucleoside reverse transcriptase inhibitor (NNRTI) rilpivirine was discussed. Primary care topics for the HIV-infected population included treatment of triglyceride level elevations and bone health. The newly published data on the proper timing of antiretroviral therapy initiation after starting tuberculosis treatment were highlighted. Finally, exciting advances in the treatment of hepatitis C virus (HCV) infection necessitate that practitioners understand the complexities of treating HIV/HCV coinfections.

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Year:  2011        PMID: 22298888      PMCID: PMC6148896     

Source DB:  PubMed          Journal:  Top Antivir Med        ISSN: 2161-5853


  29 in total

1.  Elevated triglycerides and risk of myocardial infarction in HIV-positive persons.

Authors:  Signe W Worm; David A Kamara; Peter Reiss; Ole Kirk; Wafaa El-Sadr; Christoph Fux; Eric Fontas; Andrew Phillips; Antonella D'Arminio Monforte; Stephane De Wit; Kathy Petoumenos; Nina Friis-Mller; Patrick Mercie; Jens D Lundgren; Caroline Sabin
Journal:  AIDS       Date:  2011-07-31       Impact factor: 4.177

2.  Interim guidance: preexposure prophylaxis for the prevention of HIV infection in men who have sex with men.

Authors: 
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2011-01-28       Impact factor: 17.586

3.  Integration of antiretroviral therapy with tuberculosis treatment.

Authors:  Salim S Abdool Karim; Kogieleum Naidoo; Anneke Grobler; Nesri Padayatchi; Cheryl Baxter; Andrew L Gray; Tanuja Gengiah; Santhanalakshmi Gengiah; Anushka Naidoo; Niraksha Jithoo; Gonasagrie Nair; Wafaa M El-Sadr; Gerald Friedland; Quarraisha Abdool Karim
Journal:  N Engl J Med       Date:  2011-10-20       Impact factor: 91.245

Review 4.  HIV prevention transformed: the new prevention research agenda.

Authors:  Nancy S Padian; Sandra I McCoy; Salim S Abdool Karim; Nina Hasen; Julia Kim; Michael Bartos; Elly Katabira; Stefano M Bertozzi; Bernhard Schwartländer; Myron S Cohen
Journal:  Lancet       Date:  2011-07-16       Impact factor: 79.321

5.  Rilpivirine versus efavirenz with two background nucleoside or nucleotide reverse transcriptase inhibitors in treatment-naive adults infected with HIV-1 (THRIVE): a phase 3, randomised, non-inferiority trial.

Authors:  Calvin J Cohen; Jaime Andrade-Villanueva; Bonaventura Clotet; Jan Fourie; Margaret A Johnson; Kiat Ruxrungtham; Hao Wu; Carmen Zorrilla; Herta Crauwels; Laurence T Rimsky; Simon Vanveggel; Katia Boven
Journal:  Lancet       Date:  2011-07-16       Impact factor: 79.321

Review 6.  The spectrum of engagement in HIV care and its relevance to test-and-treat strategies for prevention of HIV infection.

Authors:  Edward M Gardner; Margaret P McLees; John F Steiner; Carlos Del Rio; William J Burman
Journal:  Clin Infect Dis       Date:  2011-03-15       Impact factor: 9.079

7.  Efficacy of a nucleoside-sparing regimen of darunavir/ritonavir plus raltegravir in treatment-naive HIV-1-infected patients (ACTG A5262).

Authors:  Babafemi Taiwo; Lu Zheng; Sebastien Gallien; Roy M Matining; Daniel R Kuritzkes; Cara C Wilson; Baiba I Berzins; Edward P Acosta; Barbara Bastow; Peter S Kim; Joseph J Eron
Journal:  AIDS       Date:  2011-11-13       Impact factor: 4.177

8.  Abacavir-lamivudine versus tenofovir-emtricitabine for initial HIV-1 therapy.

Authors:  Paul E Sax; Camlin Tierney; Ann C Collier; Margaret A Fischl; Katie Mollan; Lynne Peeples; Catherine Godfrey; Nasreen C Jahed; Laurie Myers; David Katzenstein; Awny Farajallah; James F Rooney; Belinda Ha; William C Woodward; Susan L Koletar; Victoria A Johnson; P Jan Geiseler; Eric S Daar
Journal:  N Engl J Med       Date:  2009-12-01       Impact factor: 91.245

9.  Loss of bone mineral density after antiretroviral therapy initiation, independent of antiretroviral regimen.

Authors:  Todd T Brown; Grace A McComsey; Martin S King; Roula B Qaqish; Barry M Bernstein; Barbara A da Silva
Journal:  J Acquir Immune Defic Syndr       Date:  2009-08-15       Impact factor: 3.771

10.  Early antiretroviral therapy reduces AIDS progression/death in individuals with acute opportunistic infections: a multicenter randomized strategy trial.

Authors:  Andrew Zolopa; Janet Andersen; William Powderly; Alejandro Sanchez; Ian Sanne; Carol Suckow; Evelyn Hogg; Lauren Komarow
Journal:  PLoS One       Date:  2009-05-18       Impact factor: 3.240

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  1 in total

1.  Critical ventriculo-peritoneal shunt failure due to peritoneal tuberculosis: Case report and diagnostic suggestions for abdominal pseudocyst.

Authors:  Hajime Takase; Junya Tatezuki; Naoki Ikegaya; Daisuke Yamamoto; Mizuki Hashimoto; Makoto Takagi; Yasuhiko Mochimatsu; Nobutaka Kawahara
Journal:  Surg Neurol Int       Date:  2014-05-15
  1 in total

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