Literature DB >> 22298283

Treatment of Neurocritical Care Emergencies in Pregnancy.

Sangini S Sheth1, Kevin N Sheth.   

Abstract

OPINION STATEMENT: Neurologic emergencies are a major cause of morbidity and mortality in pregnant women. In part because the patient population is young, the nihilistic approach that often accompanies neurologically devastating disorders in other contexts is largely absent. A number of studies have demonstrated improved patient outcomes in the setting of aggressive care delivered by neurointensivists in a specialty-specific environment. It stands to reason that young, pregnant women who suffer from neurologically devastating disorders and who have a wide range of prognosis may also benefit from such specialized care. Close collaboration between obstetricians and neurointensivists is critical in this context. A number of unique considerations in diagnosis and management present dilemmas in the context of pregnancy, such as radiation dose from diagnostic neuroimaging, choice of pharmacotherapy for seizures, anticoagulation, and the method of delivery in the context of cerebral mass lesions and elevated intracranial pressure. Patients and their physicians are often faced with the additional challenge of balancing the relative risks and benefits of the impact of a management approach on both mother and fetus. In general, this balance tends to favor the interests of the mother, but the impact on the fetus becomes more relevant over the course of the pregnancy, especially in the third trimester. A low threshold for admission to an intensive care unit (ideally one that specializes in neurointensive care) should be used for pregnant patients. Because of the limited information regarding long-term outcomes in this population, rigid prognosis formation and early care limitations should be deferred in the immediate period. After the patient is stabilized and a plan has been charted for the remainder of the pregnancy, every effort should be made to engage patients in aggressive, urgent neurologic rehabilitation.

Entities:  

Year:  2012        PMID: 22298283     DOI: 10.1007/s11940-011-0161-6

Source DB:  PubMed          Journal:  Curr Treat Options Neurol        ISSN: 1092-8480            Impact factor:   3.598


  48 in total

1.  ACOG Committee Opinion. Number 299, September 2004 (replaces No. 158, September 1995). Guidelines for diagnostic imaging during pregnancy.

Authors: 
Journal:  Obstet Gynecol       Date:  2004-09       Impact factor: 7.661

2.  Incidence of stroke and myocardial infarction in women of reproductive age.

Authors:  D B Petitti; S Sidney; C P Quesenberry; A Bernstein
Journal:  Stroke       Date:  1997-02       Impact factor: 7.914

3.  Severe preeclampsia and the very low birth weight infant: is induction of labor harmful?

Authors:  J M Alexander; S L Bloom; D D McIntire; K J Leveno
Journal:  Obstet Gynecol       Date:  1999-04       Impact factor: 7.661

Review 4.  Diagnosis, prevention, and management of eclampsia.

Authors:  Baha M Sibai
Journal:  Obstet Gynecol       Date:  2005-02       Impact factor: 7.661

5.  Guidelines for the early management of adults with ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups: the American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists.

Authors:  Harold P Adams; Gregory del Zoppo; Mark J Alberts; Deepak L Bhatt; Lawrence Brass; Anthony Furlan; Robert L Grubb; Randall T Higashida; Edward C Jauch; Chelsea Kidwell; Patrick D Lyden; Lewis B Morgenstern; Adnan I Qureshi; Robert H Rosenwasser; Phillip A Scott; Eelco F M Wijdicks
Journal:  Stroke       Date:  2007-04-12       Impact factor: 7.914

Review 6.  Stroke and pregnancy.

Authors:  C A Davie; P O'Brien
Journal:  J Neurol Neurosurg Psychiatry       Date:  2007-11-06       Impact factor: 10.154

7.  Vascular malformations and pregnancy.

Authors:  B Sadasivan; G M Malik; C Lee; J I Ausman
Journal:  Surg Neurol       Date:  1990-05

8.  Venous thromboembolism, thrombophilia, antithrombotic therapy, and pregnancy: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).

Authors:  Shannon M Bates; Ian A Greer; Ingrid Pabinger; Shoshanna Sofaer; Jack Hirsh
Journal:  Chest       Date:  2008-06       Impact factor: 9.410

Review 9.  Pregnancy in the woman with epilepsy: maternal and fetal outcomes.

Authors:  Page B Pennell
Journal:  Semin Neurol       Date:  2002-09       Impact factor: 3.420

10.  Comparison of emergency caesarean section to misoprostol induction for the delivery of antepartum eclamptic patients: a pilot study.

Authors:  J Tukur; N I Umar; N Khan; D Musa
Journal:  Niger J Med       Date:  2007 Oct-Dec
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