Literature DB >> 22298042

Ras hitchhikes on PDE6δ.

Mark R Philips.   

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Year:  2012        PMID： 22298042      PMCID： PMC3989989          DOI： 10.1038/ncb2429

Source DB:  PubMed          Journal:  Nat Cell Biol        ISSN： 1465-7392            Impact factor:   28.824


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  14 in total

1.  The delta subunit of retinal rod cGMP phosphodiesterase regulates the membrane association of Ras and Rap GTPases.

Authors:  Vanessa Nancy; Isabelle Callebaut; Ahmed El Marjou; Jean de Gunzburg
Journal:  J Biol Chem       Date:  2002-01-10       Impact factor: 5.157

2.  The complex of Arl2-GTP and PDE delta: from structure to function.

Authors:  Michael Hanzal-Bayer; Louis Renault; Pietro Roversi; Alfred Wittinghofer; Roman C Hillig
Journal:  EMBO J       Date:  2002-05-01       Impact factor: 11.598

3.  Prenylated Rab acceptor protein is a receptor for prenylated small GTPases.

Authors:  C Figueroa; J Taylor; A B Vojtek
Journal:  J Biol Chem       Date:  2001-05-02       Impact factor: 5.157

4.  Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo.

Authors:  Shehab A Ismail; Yong-Xiang Chen; Alexandra Rusinova; Anchal Chandra; Martin Bierbaum; Lothar Gremer; Gemma Triola; Herbert Waldmann; Philippe I H Bastiaens; Alfred Wittinghofer
Journal:  Nat Chem Biol       Date:  2011-10-16       Impact factor: 15.040

5.  An acylation cycle regulates localization and activity of palmitoylated Ras isoforms.

Authors:  Oliver Rocks; Anna Peyker; Martin Kahms; Peter J Verveer; Carolin Koerner; Maria Lumbierres; Jürgen Kuhlmann; Herbert Waldmann; Alfred Wittinghofer; Philippe I H Bastiaens
Journal:  Science       Date:  2005-02-10       Impact factor: 47.728

6.  FKBP12 binds to acylated H-ras and promotes depalmitoylation.

Authors:  Ian M Ahearn; Frederick D Tsai; Helen Court; Mo Zhou; Benjamin C Jennings; Mahiuddin Ahmed; Nicole Fehrenbacher; Maurine E Linder; Mark R Philips
Journal:  Mol Cell       Date:  2011-01-21       Impact factor: 17.970

7.  Photoreceptor cGMP phosphodiesterase delta subunit (PDEdelta) functions as a prenyl-binding protein.

Authors:  Houbin Zhang; Xiao-hui Liu; Kai Zhang; Ching-Kang Chen; Jeanne M Frederick; Glenn D Prestwich; Wolfgang Baehr
Journal:  J Biol Chem       Date:  2003-10-15       Impact factor: 5.157

8.  Galectin-1(L11A) predicted from a computed galectin-1 farnesyl-binding pocket selectively inhibits Ras-GTP.

Authors:  Barak Rotblat; Hagit Niv; Sabine André; Herbert Kaltner; Hans-Joachim Gabius; Yoel Kloog
Journal:  Cancer Res       Date:  2004-05-01       Impact factor: 12.701

9.  Splice variants of SmgGDS control small GTPase prenylation and membrane localization.

Authors:  Tracy J Berg; Adam J Gastonguay; Ellen L Lorimer; John R Kuhnmuench; Rongshan Li; Alan P Fields; Carol L Williams
Journal:  J Biol Chem       Date:  2010-08-13       Impact factor: 5.157

10.  Depalmitoylated Ras traffics to and from the Golgi complex via a nonvesicular pathway.

Authors:  J Shawn Goodwin; Kimberly R Drake; Carl Rogers; Latasha Wright; Jennifer Lippincott-Schwartz; Mark R Philips; Anne K Kenworthy
Journal:  J Cell Biol       Date:  2005-07-18       Impact factor: 10.539
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  10 in total

Review 1.  Drugging the undruggable RAS: Mission possible?

Authors:  Adrienne D Cox; Stephen W Fesik; Alec C Kimmelman; Ji Luo; Channing J Der
Journal:  Nat Rev Drug Discov       Date:  2014-10-17       Impact factor: 84.694

Review 2.  Concepts and advances in cancer therapeutic vulnerabilities in RAS membrane targeting.

Authors:  James V Michael; Lawrence E Goldfinger
Journal:  Semin Cancer Biol       Date:  2017-12-02       Impact factor: 15.707

3.  Calcium causes a conformational change in lamin A tail domain that promotes farnesyl-mediated membrane association.

Authors:  Agnieszka Kalinowski; Zhao Qin; Kelli Coffey; Ravi Kodali; Markus J Buehler; Mathias Lösche; Kris Noel Dahl
Journal:  Biophys J       Date:  2013-05-21       Impact factor: 4.033

4.  Cancer: Drug for an 'undruggable' protein.

Authors:  Nicole M Baker; Channing J Der
Journal:  Nature       Date:  2013-05-22       Impact factor: 49.962

Review 5.  Post-translational modification of RAS proteins.

Authors:  Sharon L Campbell; Mark R Philips
Journal:  Curr Opin Struct Biol       Date:  2021-08-06       Impact factor: 6.809

6.  Inhibition of KRAS-dependent lung cancer cell growth by deltarasin: blockage of autophagy increases its cytotoxicity.

Authors:  Elaine Lai Han Leung; Lian Xiang Luo; Zhong Qiu Liu; Vincent Kam Wai Wong; Lin Lin Lu; Ying Xie; Ni Zhang; Yuan Qing Qu; Xing Xing Fan; Ying Li; Min Huang; Dai Kai Xiao; Jun Huang; Yan Ling Zhou; Jian Xing He; Jian Ding; Xiao Jun Yao; David C Ward; Liang Liu
Journal:  Cell Death Dis       Date:  2018-02-13       Impact factor: 8.469

Review 7.  Pleiotropic Roles of Calmodulin in the Regulation of KRas and Rac1 GTPases: Functional Diversity in Health and Disease.

Authors:  Francesc Tebar; Albert Chavero; Neus Agell; Albert Lu; Carles Rentero; Carlos Enrich; Thomas Grewal
Journal:  Int J Mol Sci       Date:  2020-05-23       Impact factor: 5.923

8.  SOAT1 promotes mevalonate pathway dependency in pancreatic cancer.

Authors:  Tobiloba E Oni; Giulia Biffi; Lindsey A Baker; Yuan Hao; Claudia Tonelli; Tim D D Somerville; Astrid Deschênes; Pascal Belleau; Chang-Il Hwang; Francisco J Sánchez-Rivera; Hilary Cox; Erin Brosnan; Abhishek Doshi; Rebecca P Lumia; Kimia Khaledi; Youngkyu Park; Lloyd C Trotman; Scott W Lowe; Alexander Krasnitz; Christopher R Vakoc; David A Tuveson
Journal:  J Exp Med       Date:  2020-09-07       Impact factor: 14.307

9.  Oncogenic KRAS engages an RSK1/NF1 pathway to inhibit wild-type RAS signaling in pancreatic cancer.

Authors:  Derek K Cheng; Tobiloba E Oni; Jennifer S Thalappillil; Youngkyu Park; Hsiu-Chi Ting; Brinda Alagesan; Nadia V Prasad; Kenneth Addison; Keith D Rivera; Darryl J Pappin; Linda Van Aelst; David A Tuveson
Journal:  Proc Natl Acad Sci U S A       Date:  2021-05-25       Impact factor: 11.205

10.  Gene Expression over Time during Cell Transformation Due to Non-Genotoxic Carcinogen Treatment of Bhas 42 Cells.

Authors:  Kiyomi Ohmori; Asuka Kamei; Yuki Watanabe; Keiko Abe
Journal:  Int J Mol Sci       Date:  2022-03-16       Impact factor: 5.923
  10 in total

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