Literature DB >> 22297917

Mental health and asthma in China: the Guangzhou Biobank Cohort Study.

Chao Qiang Jiang1, Adrian Loerbroks, Kin-bong Hubert Lam, Jos A Bosch, G Neil Thomas, Wei Sen Zhang, Kar Keung Cheng, Tai Hing Lam, Peymané Adab.   

Abstract

BACKGROUND: There is consistent evidence of the co-occurrence of poor mental health and asthma in Western populations. Since the experience and expression of mental health is partly culturally determined, it is of interest to examine if similar associations are found in other cultural settings. In that regard, very little is known about the association between mental health and asthma in Asian countries, such as China.
PURPOSE: The aim of this study was to investigate the relationship between mental health and asthma in a large sample from China.
METHOD: We used data from the Guangzhou Biobank Cohort Study phase 3 (n = 9,280). Participants reported physician-diagnosed asthma. Mental health measures included the 15-item Chinese version of the Geriatric Depression Scale (GDS-C) and the SF-12 Mental Component Summary (MCS) score. We compared the prevalence of asthma by GDS-C and MCS scores by estimating prevalence ratios (PRs) and their corresponding 95% confidence intervals (95% CI), using Poisson regression.
RESULTS: Compared to those without depression, the prevalence of asthma was higher in those with moderate or severe depression levels (PR = 2.63, 95% CI = 1.58–4.40 and PR = 4.43, 95% CI = 1.62–12.09, p for trend ≤0.0001). The prevalence of asthma increased by 46% with every 1 standard deviation increase of the GDS-C score (PR = 1.46, 95% CI = 1.24–1.73). The MCS score was not associated with asthma.
CONCLUSION: Depressive symptoms were associated with asthma prevalence in a Chinese population. Further research into the mechanism and potential directions of causality is warranted.

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Year:  2013        PMID: 22297917     DOI: 10.1007/s12529-012-9222-9

Source DB:  PubMed          Journal:  Int J Behav Med        ISSN: 1070-5503


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