Literature DB >> 22297584

Is FTO a type 2 diabetes susceptibility gene?

D Meyre1.   

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Year:  2012        PMID： 22297584     DOI： 10.1007/s00125-012-2478-4

Source DB:  PubMed          Journal:  Diabetologia        ISSN： 0012-186X            Impact factor:   10.122


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  51 in total

1.  Variation in the FTO gene locus is associated with cerebrocortical insulin resistance in humans.

Authors:  O Tschritter; H Preissl; Y Yokoyama; F Machicao; H-U Häring; A Fritsche
Journal:  Diabetologia       Date:  2007-10-05       Impact factor: 10.122

Review 2.  Increase of body weight during the first year of intensive insulin treatment in type 2 diabetes: systematic review and meta-analysis.

Authors:  A E Pontiroli; L Miele; A Morabito
Journal:  Diabetes Obes Metab       Date:  2011-11       Impact factor: 6.577

3.  Relationship between blood glucose levels and hepatic Fto mRNA expression in mice.

Authors:  Nicole J Poritsanos; Pei San Lew; Tooru M Mizuno
Journal:  Biochem Biophys Res Commun       Date:  2010-09-09       Impact factor: 3.575

4.  A better index of body adiposity.

Authors:  Richard N Bergman; Darko Stefanovski; Thomas A Buchanan; Anne E Sumner; James C Reynolds; Nancy G Sebring; Anny H Xiang; Richard M Watanabe
Journal:  Obesity (Silver Spring)       Date:  2011-03-03       Impact factor: 5.002

Review 5.  Weight beneficial treatments for type 2 diabetes.

Authors:  L F Meneghini; D Orozco-Beltran; K Khunti; S Caputo; T Damçi; A Liebl; S A Ross
Journal:  J Clin Endocrinol Metab       Date:  2011-09-07       Impact factor: 5.958

6.  The obesity-associated Fto gene is a transcriptional coactivator.

Authors:  Qiong Wu; Rudel A Saunders; Maria Szkudlarek-Mikho; Ivana de la Serna; Khew-Voon Chin
Journal:  Biochem Biophys Res Commun       Date:  2010-09-19       Impact factor: 3.575

7.  Long-range gene regulation links genomic type 2 diabetes and obesity risk regions to HHEX, SOX4, and IRX3.

Authors:  Anja Ragvin; Enrico Moro; David Fredman; Pavla Navratilova; Øyvind Drivenes; Pär G Engström; M Eva Alonso; Elisa de la Calle Mustienes; José Luis Gómez Skarmeta; Maria J Tavares; Fernando Casares; Miguel Manzanares; Veronica van Heyningen; Anders Molven; Pål R Njølstad; Francesco Argenton; Boris Lenhard; Thomas S Becker
Journal:  Proc Natl Acad Sci U S A       Date:  2009-12-22       Impact factor: 11.205

8.  A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene.

Authors:  Chris Church; Sheena Lee; Eleanor A L Bagg; James S McTaggart; Robert Deacon; Thomas Gerken; Angela Lee; Lee Moir; Jasmin Mecinović; Mohamed M Quwailid; Christopher J Schofield; Frances M Ashcroft; Roger D Cox
Journal:  PLoS Genet       Date:  2009-08-14       Impact factor: 5.917

9.  Variation in FTO contributes to childhood obesity and severe adult obesity.

Authors:  Christian Dina; David Meyre; Sophie Gallina; Emmanuelle Durand; Antje Körner; Peter Jacobson; Lena M S Carlsson; Wieland Kiess; Vincent Vatin; Cecile Lecoeur; Jérome Delplanque; Emmanuel Vaillant; François Pattou; Juan Ruiz; Jacques Weill; Claire Levy-Marchal; Fritz Horber; Natascha Potoczna; Serge Hercberg; Catherine Le Stunff; Pierre Bougnères; Peter Kovacs; Michel Marre; Beverley Balkau; Stéphane Cauchi; Jean-Claude Chèvre; Philippe Froguel
Journal:  Nat Genet       Date:  2007-05-13       Impact factor: 38.330

10.  Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits.

Authors:  Angelo Scuteri; Serena Sanna; Wei-Min Chen; Manuela Uda; Giuseppe Albai; James Strait; Samer Najjar; Ramaiah Nagaraja; Marco Orrú; Gianluca Usala; Mariano Dei; Sandra Lai; Andrea Maschio; Fabio Busonero; Antonella Mulas; Georg B Ehret; Ashley A Fink; Alan B Weder; Richard S Cooper; Pilar Galan; Aravinda Chakravarti; David Schlessinger; Antonio Cao; Edward Lakatta; Gonçalo R Abecasis
Journal:  PLoS Genet       Date:  2007-07       Impact factor: 5.917
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  11 in total

1.  Association of FTO rs9939609 SNP with Obesity and Obesity- Associated Phenotypes in a North Indian Population.

Authors:  Jai Prakash; Balraj Mittal; Apurva Srivastava; Shally Awasthi; Neena Srivastava
Journal:  Oman Med J       Date:  2016-03

Review 2.  Genetic susceptibility to type 2 diabetes and obesity: from genome-wide association studies to rare variants and beyond.

Authors:  Niels Grarup; Camilla H Sandholt; Torben Hansen; Oluf Pedersen
Journal:  Diabetologia       Date:  2014-05-24       Impact factor: 10.122

3.  Fat mass and obesity-associated gene rs11642015 polymorphism is significantly associated with prediabetes and type 2 diabetes subsequent to adjustment for body mass index.

Authors:  Liyuan Han; Linlin Tang; Changyi Wang; Zhongwei Chen; Tao Zhang; Sihan Chen; Shengyuan Liu; Xiaolin Peng; Yifeng Mai; Shiwei Duan
Journal:  Biomed Rep       Date:  2014-05-26

4.  The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis.

Authors:  Tove Fall; Sara Hägg; Reedik Mägi; Alexander Ploner; Krista Fischer; Momoko Horikoshi; Antti-Pekka Sarin; Gudmar Thorleifsson; Claes Ladenvall; Mart Kals; Maris Kuningas; Harmen H M Draisma; Janina S Ried; Natalie R van Zuydam; Ville Huikari; Massimo Mangino; Emily Sonestedt; Beben Benyamin; Christopher P Nelson; Natalia V Rivera; Kati Kristiansson; Huei-Yi Shen; Aki S Havulinna; Abbas Dehghan; Louise A Donnelly; Marika Kaakinen; Marja-Liisa Nuotio; Neil Robertson; Renée F A G de Bruijn; M Arfan Ikram; Najaf Amin; Anthony J Balmforth; Peter S Braund; Alexander S F Doney; Angela Döring; Paul Elliott; Tõnu Esko; Oscar H Franco; Solveig Gretarsdottir; Anna-Liisa Hartikainen; Kauko Heikkilä; Karl-Heinz Herzig; Hilma Holm; Jouke Jan Hottenga; Elina Hyppönen; Thomas Illig; Aaron Isaacs; Bo Isomaa; Lennart C Karssen; Johannes Kettunen; Wolfgang Koenig; Kari Kuulasmaa; Tiina Laatikainen; Jaana Laitinen; Cecilia Lindgren; Valeriya Lyssenko; Esa Läärä; Nigel W Rayner; Satu Männistö; Anneli Pouta; Wolfgang Rathmann; Fernando Rivadeneira; Aimo Ruokonen; Markku J Savolainen; Eric J G Sijbrands; Kerrin S Small; Jan H Smit; Valgerdur Steinthorsdottir; Ann-Christine Syvänen; Anja Taanila; Martin D Tobin; Andre G Uitterlinden; Sara M Willems; Gonneke Willemsen; Jacqueline Witteman; Markus Perola; Alun Evans; Jean Ferrières; Jarmo Virtamo; Frank Kee; David-Alexandre Tregouet; Dominique Arveiler; Philippe Amouyel; Marco M Ferrario; Paolo Brambilla; Alistair S Hall; Andrew C Heath; Pamela A F Madden; Nicholas G Martin; Grant W Montgomery; John B Whitfield; Antti Jula; Paul Knekt; Ben Oostra; Cornelia M van Duijn; Brenda W J H Penninx; George Davey Smith; Jaakko Kaprio; Nilesh J Samani; Christian Gieger; Annette Peters; H Erich Wichmann; Dorret I Boomsma; Eco J C de Geus; TiinaMaija Tuomi; Chris Power; Christopher J Hammond; Tim D Spector; Lars Lind; Marju Orho-Melander; Colin Neil Alexander Palmer; Andrew D Morris; Leif Groop; Marjo-Riitta Järvelin; Veikko Salomaa; Erkki Vartiainen; Albert Hofman; Samuli Ripatti; Andres Metspalu; Unnur Thorsteinsdottir; Kari Stefansson; Nancy L Pedersen; Mark I McCarthy; Erik Ingelsson; Inga Prokopenko
Journal:  PLoS Med       Date:  2013-06-25       Impact factor: 11.069

5.  Longitudinal relationships between glycemic status and body mass index in a multiethnic study: evidence from observational and genetic epidemiology.

Authors:  Adeola F Ishola; Hertzel C Gerstein; James C Engert; Viswanathan Mohan; Rafael Diaz; Sonia S Anand; David Meyre
Journal:  Sci Rep       Date:  2016-08-02       Impact factor: 4.379

6.  Associations of the FTO rs9939609 and the MC4R rs17782313 polymorphisms with type 2 diabetes are modulated by diet, being higher when adherence to the Mediterranean diet pattern is low.

Authors:  Carolina Ortega-Azorín; Jose V Sorlí; Eva M Asensio; Oscar Coltell; Miguel Ángel Martínez-González; Jordi Salas-Salvadó; Maria-Isabel Covas; Fernando Arós; José Lapetra; Lluís Serra-Majem; Enrique Gómez-Gracia; Miquel Fiol; Guillermo Sáez-Tormo; Xavier Pintó; Miguel Angel Muñoz; Emilio Ros; Jose M Ordovás; Ramon Estruch; Dolores Corella
Journal:  Cardiovasc Diabetol       Date:  2012-11-06       Impact factor: 9.951

7.  Replication of type 2 diabetes candidate genes variations in three geographically unrelated Indian population groups.

Authors:  Shafat Ali; Rupali Chopra; Siddharth Manvati; Yoginder Pal Singh; Nabodita Kaul; Anita Behura; Ankit Mahajan; Prabodh Sehajpal; Subash Gupta; Manoj K Dhar; Gagan B N Chainy; Amarjit S Bhanwer; Swarkar Sharma; Rameshwar N K Bamezai
Journal:  PLoS One       Date:  2013-03-19       Impact factor: 3.240

8.  BMI-associated alleles do not constitute risk alleles for polycystic ovary syndrome independently of BMI: a case-control study.

Authors:  Yvonne V Louwers; Nigel W Rayner; Blanca M Herrera; Lisette Stolk; Christopher J Groves; Thomas M Barber; Andre G Uitterlinden; Stephen Franks; Joop S E Laven; Mark I McCarthy
Journal:  PLoS One       Date:  2014-01-31       Impact factor: 3.240

9.  FTO Gene Polymorphism Is Associated with Type 2 Diabetes through Its Effect on Increasing the Maximum BMI in Japanese Men.

Authors:  Yutaka Kamura; Minoru Iwata; Shiro Maeda; Satomi Shinmura; Yukiko Koshimizu; Hisae Honoki; Kazuhito Fukuda; Manabu Ishiki; Isao Usui; Yasuo Fukushima; Atsuko Takano; Hiromi Kato; Shihou Murakami; Kiyohiro Higuchi; Chikaaki Kobashi; Kazuyuki Tobe
Journal:  PLoS One       Date:  2016-11-07       Impact factor: 3.240

10.  Effect of FTO rs9939609 variant on insulin resistance in obese female adolescents.

Authors:  Kristy Iskandar; Suryono Yudha Patria; Emy Huriyati; Harry Freitag Luglio; Madarina Julia; Rina Susilowati
Journal:  BMC Res Notes       Date:  2018-05-15
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