Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Copper-catalyzed aerobic [3+2]-annulation of N-alkenyl amidines.

Literature DB >> 22296256

Copper-catalyzed aerobic [3+2]-annulation of N-alkenyl amidines.

Abstract

A method for the synthesis of bi- and tricyclic amidines has been developed through copper-catalyzed aerobic [3+2]-annulation reaction of N-alkenyl amidines. These cyclic amidines could be converted into mono-benzyl-protected vicinal diamines by the reduction with aluminum hydride.

Entities: Chemical

Mesh：

Substances：
Amidines
Copper

Year: 2012 PMID： 22296256 DOI： 10.1021/ja2120629

Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419

Keyword Cloud
Cited

11 in total

Review 1. Aerobic copper-catalyzed organic reactions.

Authors: Scott E Allen; Ryan R Walvoord; Rosaura Padilla-Salinas; Marisa C Kozlowski
Journal: Chem Rev Date: 2013-06-20 Impact factor: 60.622

2. Stereoselective Synthesis of Cyclic Guanidines by Directed Diamination of Unactivated Alkenes.

Authors: Artur K Mailyan; Kyle Young; Joanna L Chen; Bradley T Reid; Armen Zakarian
Journal: Org Lett Date: 2016-10-25 Impact factor: 6.005

3. Copper-promoted synthesis of 1,4-benzodiazepinones via alkene diamination.

Authors: Shuklendu D Karyakarte; Fatima C Sequeira; Garrick H Zibreg; Guoqing Huang; Josiah P Matthew; Marina M M Ferreira; Sherry R Chemler
Journal: Tetrahedron Lett Date: 2015-06-03 Impact factor: 2.415

4. Copper-Catalyzed Alkene Aminoazidation as a Rapid Entry to 1,2-Diamines and Installation of an Azide Reporter onto Azahetereocycles.

Authors: Kun Shen; Qiu Wang
Journal: J Am Chem Soc Date: 2017-09-05 Impact factor: 15.419

10. Visible-light enabled room-temperature dealkylative imidation of secondary and tertiary amines promoted by aerobic ruthenium catalysis.

Authors: Dong Yang; Jingqi Shi; Jiaming Chen; Xiaoqi Jia; Cuiying Shi; Lifang Ma; Ziyuan Li
Journal: RSC Adv Date: 2021-05-25 Impact factor: 4.036

Copper-catalyzed aerobic [3+2]-annulation of N-alkenyl amidines.

Review 1. Aerobic copper-catalyzed organic reactions.

2. Stereoselective Synthesis of Cyclic Guanidines by Directed Diamination of Unactivated Alkenes.

3. Copper-promoted synthesis of 1,4-benzodiazepinones via alkene diamination.

4. Copper-Catalyzed Alkene Aminoazidation as a Rapid Entry to 1,2-Diamines and Installation of an Azide Reporter onto Azahetereocycles.

5. Copper-Catalyzed Alkene Diamination: Synthesis of Chiral 2-Aminomethyl Indolines and Pyrrolidines.

6. Cu(I)-catalyzed sequential diamination and dehydrogenation of terminal olefins: a facile approach to imidazolinones.

7. Catalytic diamination of olefins via N-N bond activation.

8. Efficient Copper-Catalyzed Multicomponent Synthesis of N-Acyl Amidines via Acyl Nitrenes.

9. Catalyst-free one-pot, four-component approach for the synthesis of di- and tri-substituted N-sulfonyl formamidines.

10. Visible-light enabled room-temperature dealkylative imidation of secondary and tertiary amines promoted by aerobic ruthenium catalysis.