OBJECTIVE: Takotsubo cardiomyopathy (TC) mimics myocardial infarction and is well defined and known to not only Japan but also western countries. However, whether or not there are differences in the characteristics of TC between Japan and USA remains unknown. PATIENTS: Data for patients who had undergone urgent left heart catheterization for suspected acute coronary syndrome were retrospectively retrieved from Keio University School of Medicine (KUSM) database in Japan and Lahey Clinic Medical Center (LCMC) database in USA between 2002 and 2007. RESULTS: During the study period, 626 coronary angiographies were performed in KUSM and 1,880 coronary angiographies were performed in LCMC. Twelve patients in Japan and 34 patients in USA met the inclusion criteria. Mean age of patients in Japan was 75 years where 92% were women, compared to 67 years and 94% women in USA. Although the prevalence of hypertension, dyslipidemia and diabetes mellitus were similar between Japan and USA, there was a trend towards fewer patients in Japan displaying a history of coronary revascularization. Surprisingly, a family history of premature coronary artery disease (CAD) was present in 21% of USA patients, whereas no patients were present in Japan. There were no differences in the incidence of readmission for heart failure, cardiac death and TC recurrence during the follow-up period. CONCLUSION: Patients with TC in Japan have fewer prior overt CAD and fewer family history of premature CAD, but no significant differences were found in the long-term prognosis and the recurrence rate between patients in Japan and USA.
OBJECTIVE:Takotsubo cardiomyopathy (TC) mimics myocardial infarction and is well defined and known to not only Japan but also western countries. However, whether or not there are differences in the characteristics of TC between Japan and USA remains unknown. PATIENTS: Data for patients who had undergone urgent left heart catheterization for suspected acute coronary syndrome were retrospectively retrieved from Keio University School of Medicine (KUSM) database in Japan and Lahey Clinic Medical Center (LCMC) database in USA between 2002 and 2007. RESULTS: During the study period, 626 coronary angiographies were performed in KUSM and 1,880 coronary angiographies were performed in LCMC. Twelve patients in Japan and 34 patients in USA met the inclusion criteria. Mean age of patients in Japan was 75 years where 92% were women, compared to 67 years and 94% women in USA. Although the prevalence of hypertension, dyslipidemia and diabetes mellitus were similar between Japan and USA, there was a trend towards fewer patients in Japan displaying a history of coronary revascularization. Surprisingly, a family history of premature coronary artery disease (CAD) was present in 21% of USA patients, whereas no patients were present in Japan. There were no differences in the incidence of readmission for heart failure, cardiac death and TC recurrence during the follow-up period. CONCLUSION:Patients with TC in Japan have fewer prior overt CAD and fewer family history of premature CAD, but no significant differences were found in the long-term prognosis and the recurrence rate between patients in Japan and USA.
Authors: Yoichi Imori; Ken Kato; Jelena R Ghadri; Christian Templin; Victoria L Cammann; Konrad A Szawan; Manfred Wischnewsky; Sara Dreiding; Michael Würdinger; Maximilian Schönberger; Vanya Petkova; David Niederseer; Rena A Levinson; Davide Di Vece; Sebastiano Gili; Burkhardt Seifert; Masaki Wakita; Noriko Suzuki; Rodolfo Citro; Eduardo Bossone; Susanne Heiner; Maike Knorr; Thomas Jansen; Thomas Münzel; Fabrizio D'Ascenzo; Jennifer Franke; Ioana Sorici-Barb; Hugo A Katus; Annahita Sarcon; Jerold Shinbane; L Christian Napp; Johann Bauersachs; Milosz Jaguszewski; Reiko Shiomura; Shunichi Nakamura; Hitoshi Takano; Michel Noutsias; Christof Burgdorf; Iwao Ishibashi; Toshiharu Himi; Wolfgang Koenig; Heribert Schunkert; Holger Thiele; Behrouz Kherad; Carsten Tschöpe; Burkert M Pieske; Lawrence Rajan; Guido Michels; Roman Pfister; Shingo Mizuno; Alessandro Cuneo; Claudius Jacobshagen; Gerd Hasenfuß; Mahir Karakas; Hiroki Mochizuki; Alexander Pott; Wolfgang Rottbauer; Samir M Said; Ruediger C Braun-Dullaeus; Adrian Banning; Toshiaki Isogai; Akihisa Kimura; Florim Cuculi; Richard Kobza; Thomas A Fischer; Tuija Vasankari; K E Juhani Airaksinen; Yasuhiro Tomita; Monika Budnik; Grzegorz Opolski; Rafal Dworakowski; Philip MacCarthy; Christoph Kaiser; Stefan Osswald; Leonarda Galiuto; Filippo Crea; Wolfgang Dichtl; Tsutomu Murakami; Yuji Ikari; Klaus Empen; Daniel Beug; Stephan B Felix; Clément Delmas; Olivier Lairez; Tetsuo Yamaguchi; Ibrahim El-Battrawy; Ibrahim Akin; Martin Borggrefe; John D Horowitz; Martin Kozel; Petr Tousek; Petr Widimský; Ekaterina Gilyarova; Alexandra Shilova; Mikhail Gilyarov; Michael Neuhaus; Philippe Meyer; Jose David Arroja; Christina Chan; Paul Bridgman; Jan Galuszka; Gregor Poglajen; Pedro Carrilho-Ferreira; Fausto J Pinto; Christian Hauck; Lars S Maier; Kan Liu; Carlo Di Mario; Carla Paolini; Claudio Bilato; Matteo Bianco; Lucas Jörg; Hans Rickli; David E Winchester; Christian Ukena; Michael Böhm; Jeroen J Bax; Abhiram Prasad; Charanjit S Rihal; Shigeru Saito; Yoshio Kobayashi; Thomas F Lüscher; Frank Ruschitzka; Wataru Shimizu Journal: Clin Res Cardiol Date: 2021-05-19 Impact factor: 5.460