Literature DB >> 22293269

Epigenetic changes in tumor microenvironment.

P Dey1.   

Abstract

The drama of cancer is not the solo performance of the malignant cells. Microenvironment of the tumor has significant contribution in carcinogenesis. Recent evidences show distinct gene promoter methylation in stromal cells of various malignant and pre-malignant tumors. These changes probably create unique tumor microenvironment, which is responsible for initiation, proliferation, invasion, and metastasis of tumor cells. In this mini review the role of epigenetic changes of tumor microenvironment in carcinogenesis has been discussed.

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Year:  2011        PMID： 22293269     DOI： 10.4103/0019-509X.92246

Source DB:  PubMed          Journal:  Indian J Cancer        ISSN： 0019-509X            Impact factor:   1.224


  7 in total

1.  Transcriptional coexpression network reveals the involvement of varying stem cell features with different dysregulations in different gastric cancer subtypes.

Authors:  Kalaivani Kalamohan; Jayaprakash Periasamy; Divya Bhaskar Rao; Georgina D Barnabas; Srigayatri Ponnaiyan; Kumaresan Ganesan
Journal:  Mol Oncol       Date:  2014-05-09       Impact factor: 6.603

2.  Glioma revisited: from neurogenesis and cancer stem cells to the epigenetic regulation of the niche.

Authors:  Felipe de Almeida Sassi; Algemir Lunardi Brunetto; Gilberto Schwartsmann; Rafael Roesler; Ana Lucia Abujamra
Journal:  J Oncol       Date:  2012-07-08       Impact factor: 4.375

3.  DNA methylation-mediated silencing of matricellular protein dermatopontin promotes hepatocellular carcinoma metastasis by α3β1 integrin-Rho GTPase signaling.

Authors:  Ying Fu; Ming-Xuan Feng; Jian Yu; Ming-Ze Ma; Xiao-Jin Liu; Jun Li; Xiao-Mei Yang; Ya-Hui Wang; Yan-Li Zhang; Jun-Ping Ao; Feng Xue; Wenxin Qin; Jianren Gu; Qiang Xia; Zhi-Gang Zhang
Journal:  Oncotarget       Date:  2014-08-30

4.  Genetic alterations and epigenetic alterations of cancer-associated fibroblasts.

Authors:  Heng Du; Guowei Che
Journal:  Oncol Lett       Date:  2016-11-30       Impact factor: 2.967

5.  DNA Methylation-Mediated Silencing of Regenerating Protein 1 Alpha (REG1A) Affects Gastric Cancer Prognosis.

Authors:  Yan-Song Qiu; Guang-Jun Liao; Ning-Ning Jiang
Journal:  Med Sci Monit       Date:  2017-12-09

6.  Transcriptomic analyses identify key differentially expressed genes and clinical outcomes between triple-negative and non-triple-negative breast cancer.

Authors:  Bo Chen; Hailin Tang; Xi Chen; Guochun Zhang; Yulei Wang; Xiaoming Xie; Ning Liao
Journal:  Cancer Manag Res       Date:  2018-12-21       Impact factor: 3.989

Review 7.  Epigenetic changes in fibroblasts drive cancer metabolism and differentiation.

Authors:  Rajeev Mishra; Subhash Haldar; Surabhi Suchanti; Neil A Bhowmick
Journal:  Endocr Relat Cancer       Date:  2019-12       Impact factor: 5.678
  7 in total

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