Literature DB >> 22290940

Emergence of OXA-48-type carbapenemase-producing Enterobacteriaceae in German hospitals.

Yvonne Pfeifer1, Kathrin Schlatterer, Elisabeth Engelmann, Reinhold A Schiller, Hans Reiner Frangenberg, Doris Stiewe, Martin Holfelder, Wolfgang Witte, Patrice Nordmann, Laurent Poirel.   

Abstract

Nine carbapenem-resistant Enterobacteriaceae isolates collected from eight patients in five German hospitals were investigated. Six isolates produced the OXA-48 carbapenemase, and three isolates produced OXA-162, which is a point mutant form of OXA-48. Both carbapenemase genes were located on IncL/M-type conjugative plasmids. Insertion sequence IS1999 (truncated or not by IS1R) was located upstream of the bla(OXA-48) and bla(OXA-162) genes in all of the isolates. Pulsed-field gel electrophoresis typing indicated the clonal transmission of an OXA-48-producing Klebsiella pneumoniae strain in two hospitals.

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Year:  2012        PMID: 22290940      PMCID: PMC3318349          DOI: 10.1128/AAC.05315-11

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  18 in total

1.  Genetic features of the widespread plasmid coding for the carbapenemase OXA-48.

Authors:  Laurent Poirel; Rémy A Bonnin; Patrice Nordmann
Journal:  Antimicrob Agents Chemother       Date:  2011-11-14       Impact factor: 5.191

Review 2.  Emerging carbapenemases: a global perspective.

Authors:  Timothy R Walsh
Journal:  Int J Antimicrob Agents       Date:  2010-11       Impact factor: 5.283

3.  Functional characterization of IS1999, an IS4 family element involved in mobilization and expression of beta-lactam resistance genes.

Authors:  Daniel Aubert; Thierry Naas; Claire Héritier; Laurent Poirel; Patrice Nordmann
Journal:  J Bacteriol       Date:  2006-09       Impact factor: 3.490

4.  Spread of OXA-48-encoding plasmid in Turkey and beyond.

Authors:  Amélie Carrër; Laurent Poirel; Mesut Yilmaz; Ozay Arikan Akan; Cilli Feriha; Gaëlle Cuzon; Ghassan Matar; Patrick Honderlick; Patrice Nordmann
Journal:  Antimicrob Agents Chemother       Date:  2010-01-19       Impact factor: 5.191

5.  Collateral damage of flomoxef therapy: in vivo development of porin deficiency and acquisition of blaDHA-1 leading to ertapenem resistance in a clinical isolate of Klebsiella pneumoniae producing CTX-M-3 and SHV-5 beta-lactamases.

Authors:  Chen-Hsiang Lee; Chishih Chu; Jien-Wei Liu; Yi-Shung Chen; Chiung-Jung Chiu; Lin-Hui Su
Journal:  J Antimicrob Chemother       Date:  2007-06-18       Impact factor: 5.790

6.  Carbapenem-resistant Escherichia coli and Klebsiella pneumoniae isolates from Turkey with OXA-48-like carbapenemases and outer membrane protein loss.

Authors:  Dolunay Gülmez; Neil Woodford; Marie-France I Palepou; Shazad Mushtaq; Gokhan Metan; Yusuf Yakupogullari; Sesin Kocagoz; Omrum Uzun; Gulsen Hascelik; David M Livermore
Journal:  Int J Antimicrob Agents       Date:  2008-03-12       Impact factor: 5.283

7.  Emergence of carbapenem-non-susceptible extended-spectrum beta-lactamase-producing Klebsiella pneumoniae isolates at the university hospital of Tübingen, Germany.

Authors:  Sabine Gröbner; Dirk Linke; Wolfgang Schütz; Claudia Fladerer; Johannes Madlung; Ingo B Autenrieth; Wolfgang Witte; Yvonne Pfeifer
Journal:  J Med Microbiol       Date:  2009-06-05       Impact factor: 2.472

8.  Emergence of oxacillinase-mediated resistance to imipenem in Klebsiella pneumoniae.

Authors:  Laurent Poirel; Claire Héritier; Venus Tolün; Patrice Nordmann
Journal:  Antimicrob Agents Chemother       Date:  2004-01       Impact factor: 5.191

Review 9.  Diversity, epidemiology, and genetics of class D beta-lactamases.

Authors:  Laurent Poirel; Thierry Naas; Patrice Nordmann
Journal:  Antimicrob Agents Chemother       Date:  2009-08-31       Impact factor: 5.191

10.  Salmonella enterica serovar Typhi with CTX-M beta-lactamase, Germany.

Authors:  Yvonne Pfeifer; Jens Matten; Wolfgang Rabsch
Journal:  Emerg Infect Dis       Date:  2009-09       Impact factor: 6.883

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  30 in total

1.  Rapid Detection of OXA-48-Producing Enterobacteriaceae by Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry.

Authors:  Marina Oviaño; Maria José Barba; Begoña Fernández; Adriana Ortega; Belén Aracil; Jesús Oteo; José Campos; Germán Bou
Journal:  J Clin Microbiol       Date:  2015-12-16       Impact factor: 5.948

2.  Emergence of OXA-162 Carbapenemase- and DHA-1 AmpC Cephalosporinase-Producing Sequence Type 11 Klebsiella pneumoniae Causing Community-Onset Infection in Greece.

Authors:  Evangelia Voulgari; Aggeliki Poulou; Evangelia Dimitroulia; Lida Politi; Kyriaki Ranellou; Vassiliki Gennimata; Fani Markou; Spyros Pournaras; Athanassios Tsakris
Journal:  Antimicrob Agents Chemother       Date:  2015-12-14       Impact factor: 5.191

3.  Detection of NDM-1, VIM-1, KPC, OXA-48, and OXA-162 carbapenemases by matrix-assisted laser desorption ionization-time of flight mass spectrometry.

Authors:  Jaroslav Hrabák; Vendula Studentová; Radka Walková; Helena Zemlicková; Vladislav Jakubu; Eva Chudácková; Marek Gniadkowski; Yvonne Pfeifer; John D Perry; Kathryn Wilkinson; Tamara Bergerová
Journal:  J Clin Microbiol       Date:  2012-05-02       Impact factor: 5.948

4.  Derepressed transfer properties leading to the efficient spread of the plasmid encoding carbapenemase OXA-48.

Authors:  Anaïs Potron; Laurent Poirel; Patrice Nordmann
Journal:  Antimicrob Agents Chemother       Date:  2013-11-04       Impact factor: 5.191

5.  Matrix-assisted laser desorption ionization-time of flight mass spectrometry meropenem hydrolysis assay with NH4HCO3, a reliable tool for direct detection of carbapenemase activity.

Authors:  Costas C Papagiannitsis; Vendula Študentová; Radoslaw Izdebski; Olga Oikonomou; Yvonne Pfeifer; Efthimia Petinaki; Jaroslav Hrabák
Journal:  J Clin Microbiol       Date:  2015-02-18       Impact factor: 5.948

6.  Findings from an outbreak of carbapenem-resistant Klebsiella pneumoniae emphasize the role of antibiotic treatment for cross transmission.

Authors:  Stefan Borgmann; Yvonne Pfeifer; Laura Becker; Beate Rieß; Rabea Siegmund; Ulrich Sagel
Journal:  Infection       Date:  2017-11-24       Impact factor: 3.553

Review 7.  Raoultella spp.-clinical significance, infections and susceptibility to antibiotics.

Authors:  Alicja Sękowska
Journal:  Folia Microbiol (Praha)       Date:  2017-01-06       Impact factor: 2.099

8.  Prospective multicenter study of carbapenemase-producing Enterobacteriaceae from 83 hospitals in Spain reveals high in vitro susceptibility to colistin and meropenem.

Authors:  Jesús Oteo; Adriana Ortega; Rosa Bartolomé; Germán Bou; Carmen Conejo; Marta Fernández-Martínez; Juan José González-López; Laura Martínez-García; Luis Martínez-Martínez; María Merino; Elisenda Miró; Marta Mora; Ferran Navarro; Antonio Oliver; Álvaro Pascual; Jesús Rodríguez-Baño; Guillermo Ruiz-Carrascoso; Patricia Ruiz-Garbajosa; Laura Zamorano; Verónica Bautista; María Pérez-Vázquez; José Campos
Journal:  Antimicrob Agents Chemother       Date:  2015-03-30       Impact factor: 5.191

9.  Molecular Characterization of OXA-48-Like-Producing Enterobacteriaceae in the Czech Republic and Evidence for Horizontal Transfer of pOXA-48-Like Plasmids.

Authors:  Anna Skalova; Katerina Chudejova; Veronika Rotova; Matej Medvecky; Vendula Studentova; Eva Chudackova; Pavel Lavicka; Tamara Bergerova; Vladislav Jakubu; Helena Zemlickova; Costas C Papagiannitsis; Jaroslav Hrabak
Journal:  Antimicrob Agents Chemother       Date:  2017-01-24       Impact factor: 5.191

10.  Whole-Genome Analysis of an Extensively Drug-Resistance Empedobacter falsenii Strain Reveals Distinct Features and the Presence of a Novel Metallo-ß-Lactamase (EBR-2).

Authors:  Chelsea Collins; Marisa Almuzara; Mariana Saigo; Sabrina Montaña; Kevin Chiem; German Traglia; Maria Alejandra Mussi; Marcelo Tolmasky; Andres Iriarte; Carlos Vay; Maria Soledad Ramirez
Journal:  Curr Microbiol       Date:  2018-04-23       Impact factor: 2.188

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