Literature DB >> 22290632

Diagnosis and treatment of diffuse large B-cell lymphoma.

Ulrich Mey1, Felicitas Hitz, Andreas Lohri, Stefanie Pederiva, Christian Taverna, Alexander Tzankov, Oliver Meier, Karen Yeow, Christoph Renner.   

Abstract

Diffuse large B-cell lymphoma (DLBCL) is the most frequently-occurring type of malignant lymphoma in the Western world. It has an aggressive natural history, with a median survival of less than one year if left untreated. Immunochemotherapy regimens, consisting of the anti-CD20 antibody rituximab typically in combination with cyclophosphamide, doxorubicin, vincristine and prednisone (CHOP), are currently the treatment backbone. Despite remarkable progress in improving patient survival, clinical outcomes are still unsatisfactory for certain subsets of patients, including the elderly and very elderly and those with highly aggressive disease. This review outlines some of the current treatment strategies for DLBCL and discusses the main issues that affect clinical practice.

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Year:  2012        PMID： 22290632     DOI： 10.4414/smw.2012.13511

Source DB:  PubMed          Journal:  Swiss Med Wkly        ISSN： 0036-7672            Impact factor:   2.193


  11 in total

Review 1.  Assessment of Correlation Between Early and Late Efficacy Endpoints to Identify Potential Surrogacy Relationships in Non-Hodgkin Lymphoma: a Literature-Based Meta-analysis of 108 Phase II and Phase III Studies.

Authors:  Rui Zhu; Dan Lu; Yu-Waye Chu; Akiko Chai; Michelle Green; Nancy Zhang; Jin Yan Jin
Journal:  AAPS J       Date:  2017-02-21       Impact factor: 4.009

2.  The Roles of Exosomal microRNAs in Diffuse Large B-Cell Lymphoma: Diagnosis, Prognosis, Clinical Application, and Biomolecular Mechanisms.

Authors:  Somayeh Yazdanparast; Zoufang Huang; Shayan Keramat; Mehrdad Izadirad; Yi-Dong Li; Letao Bo; Ahmad Gharehbaghian; Zhe-Sheng Chen
Journal:  Front Oncol       Date:  2022-06-02       Impact factor: 5.738

3.  Determining protein biomarkers for DLBCL using FFPE tissues from HIV negative and HIV positive patients.

Authors:  Pumza Magangane; Raveendra Sookhayi; Dhirendra Govender; Richard Naidoo
Journal:  J Mol Histol       Date:  2016-10-01       Impact factor: 2.611

4.  NonHodgkin's Lymphoma with Peritoneal Localization.

Authors:  E Curakova; M Genadieva-Dimitrova; J Misevski; V Caloska-Ivanova; V Andreevski; B Todorovska; U Isahi; M Trajkovska; P Misevska; N Joksimovic; S Genadieva-Stavric; S Antovic; N Jankulovski
Journal:  Case Rep Gastrointest Med       Date:  2014-03-09

5.  Dissecting the regulatory microenvironment of a large animal model of non-Hodgkin lymphoma: evidence of a negative prognostic impact of FOXP3+ T cells in canine B cell lymphoma.

Authors:  Dammy Pinheiro; Yu-Mei Chang; Hannah Bryant; Balazs Szladovits; Tim Dalessandri; Lucy J Davison; Elizabeth Yallop; Emily Mills; Chiara Leo; Ana Lara; Anneliese Stell; Gerry Polton; Oliver A Garden
Journal:  PLoS One       Date:  2014-08-13       Impact factor: 3.240

6.  Prognostic efficacy of the human B-cell lymphoma prognostic genes in predicting disease-free survival (DFS) in the canine counterpart.

Authors:  Mohamad Zamani-Ahmadmahmudi; Sina Aghasharif; Keyhan Ilbeigi
Journal:  BMC Vet Res       Date:  2017-01-09       Impact factor: 2.741

7.  Diffuse large B-cell lymphoma mimicking chronic osteomyelitis of the ankle joint: A case report.

Authors:  Emam M Kheder; Hussain H Sharahlii; Saad M AlSubaie; Mushref A Algarni; Hussain Al Omar
Journal:  SAGE Open Med Case Rep       Date:  2021-02-15

8.  Large B-cell lymphoma mimicking iliopsoas abscess following open revision of proximal femur infected non-union: a case report.

Authors:  James McCammon; Randy Mascarenhas; Michael J Monument; Abdul Elyousfi; Brad Pilkey
Journal:  BMC Res Notes       Date:  2014-07-23

9.  Highly efficient, in-vivo Fas-mediated apoptosis of B-cell lymphoma by hexameric CTLA4-FasL.

Authors:  Alexandra Aronin; Shira Amsili; Tatyana B Prigozhina; Kobi Tzdaka; Roy Shen; Leonid Grinmann; Fanny Szafer; Per Edebrink; Mari-Anne Rauvola; Noam Shani; Michal Dranitzki Elhalel
Journal:  J Hematol Oncol       Date:  2014-09-17       Impact factor: 17.388

10.  The Comparative Diagnostic Features of Canine and Human Lymphoma.

Authors:  Davis M Seelig; Anne C Avery; E J Ehrhart; Michael A Linden
Journal:  Vet Sci       Date:  2016-06-09
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