Literature DB >> 22289087

An endogenous bile acid and dietary sucrose from skin secretions of alkaloid-sequestering poison frogs.

Valerie C Clark1, Liva Harinantenaina, Martin Zeller, William Ronto, James Rocca, Aaron T Dossey, Daniel Rakotondravony, David G I Kingston, Chris Shaw.   

Abstract

The skins of Madagascar poison frogs (Mantella) and certain Neotropical poison frogs (Epipedobates, Dendrobates) secrete the new bile acid tauromantellic acid (1), which was found in both wild-caught and captive-born frogs. This is the first molecule of endogenous origin detected in skin secretions from these taxa. Sucrose was also detected in secretions from wild-caught Mantella but not in captive-born frogs, suggesting a dietary origin.

Entities:  

Mesh：

Substances：

Year:  2012        PMID： 22289087      PMCID： PMC3311751          DOI： 10.1021/np200963r

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  20 in total

1.  Discovery of skin alkaloids in a miniaturized eleutherodactylid frog from Cuba.

Authors:  Ariel Rodríguez; Dennis Poth; Stefan Schulz; Miguel Vences
Journal:  Biol Lett       Date:  2010-11-03       Impact factor: 3.703

2.  Bile salts of anura.

Authors:  T Kuramoto; H Kikuchi; H Sanemori; T Hoshita
Journal:  Chem Pharm Bull (Tokyo)       Date:  1973-05       Impact factor: 1.645

3.  Batrachotoxin. The active principle of the Colombian arrow poison frog, Phyllobates bicolor.

Authors:  J W Daly; B Witkop; P Bommer; K Biemann
Journal:  J Am Chem Soc       Date:  1965-01-05       Impact factor: 15.419

4.  Morphology of the granular secretory glands in skin of poison-dart frogs (Dendrobatidae).

Authors:  M Neuwirth; J W Daly; C W Myers; L W Tice
Journal:  Tissue Cell       Date:  1979       Impact factor: 2.466

Review 5.  Further classification of skin alkaloids from neotropical poison frogs (Dendrobatidae), with a general survey of toxic/noxious substances in the amphibia.

Authors:  J W Daly; C W Myers; N Whittaker
Journal:  Toxicon       Date:  1987       Impact factor: 3.033

6.  Mixed oxo-hydroxy bile acids as actual or potential impurities in ursodeoxycholic acid preparation: a 1H and 13C NMR study.

Authors:  L Bettarello; O Bortolini; G Fantin; A Guerrini
Journal:  Farmaco       Date:  2000-01

7.  Comparison of the bile salts of frogs with those of their tadpoles. Bile-salt changes during the metamorphosis of Rana Catesbeiana Shaw.

Authors:  I G Anderson; T Briggs; G A Haslewood; R S Oldham; H Schären; L Tökés
Journal:  Biochem J       Date:  1979-12-01       Impact factor: 3.857

8.  Evidence for an enantioselective pumiliotoxin 7-hydroxylase in dendrobatid poison frogs of the genus Dendrobates.

Authors:  John W Daly; H Martin Garraffo; Thomas F Spande; Valerie C Clark; Jingyuan Ma; Herman Ziffer; John F Cover
Journal:  Proc Natl Acad Sci U S A       Date:  2003-09-05       Impact factor: 11.205

9.  Metabolism of C26 bile alcohols in the bullfrog, Rana catesbeiana.

Authors:  Y Noma; K Kihira; T Kuramoto; T Hoshita
Journal:  Steroids       Date:  1988 Mar-Apr       Impact factor: 2.668

10.  A more detailed study of bile salt evolution, including techniques for small-scale identification and their application to amphibian biles.

Authors:  I G Anderson; G A Haslewood; R S Oldham; B Amos; L Tökés
Journal:  Biochem J       Date:  1974-08       Impact factor: 3.857
View more
  2 in total

1.  Bicyclic C21 terpenoids from the marine sponge Clathria compressa.

Authors:  Prasoon Gupta; Upasana Sharma; Thomas C Schulz; Amanda B McLean; Allan J Robins; Lyndon M West
Journal:  J Nat Prod       Date:  2012-05-18       Impact factor: 4.050

2.  Activation of the Bile Acid Pathway and No Observed Antimicrobial Peptide Sequences in the Skin of a Poison Frog.

Authors:  Megan L Civitello; Robert Denton; Michael A Zasloff; John H Malone
Journal:  G3 (Bethesda)       Date:  2019-02-07       Impact factor: 3.154
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.