Literature DB >> 22288601

Gore Bio-A® Fistula Plug: a new sphincter-sparing procedure for complex anal fistula.

C Ratto1, F Litta, A Parello, L Donisi, G Zaccone, V De Simone.   

Abstract

AIM: The surgical treatment of a complex anal fistula remains controversial, although 'sphincter-saving' operations are desirable. The Gore Bio-A® Fistula Plug is a new bioprosthetic plug that has been proposed for the treatment of complex anal fistula. This study reports preliminary data following implantation of this plug.
METHOD: Eleven patients with a complex anal fistula underwent insertion of Gore Bio-A® Fistula Plugs. The disc diameter and number of tubes in the plug were adapted to the fistula to allow accommodation of the disc into a submucosal pocket, and the excess tubes were trimmed. During the follow-up period, patients underwent clinical and physical examinations and three-dimensional endoanal ultrasound.
RESULTS: Fistulas were high anterior transphincteric in five patients and high posterior transphincteric in six patients. All patients had a loose seton placement before plug insertion. Two, three and four tubes were inserted into the fistula plug in seven, three and one patient, respectively. The median follow-up period was 5 months. No patient reported any faecal incontinence. There was no case of early plug dislodgement. Treatment success was noted for eight (72.7%) of 11 patients at the last follow-up appointment.
CONCLUSION: Implanting a Gore Bio-A® Fistula Plug is a simple, minimally invasive, safe and potentially effective procedure to treat complex anal fistula. Patient selection is fundamental for success.
© 2012 The Authors. Colorectal Disease © 2012 The Association of Coloproctology of Great Britain and Ireland.

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Year:  2012        PMID: 22288601     DOI: 10.1111/j.1463-1318.2012.02964.x

Source DB:  PubMed          Journal:  Colorectal Dis        ISSN: 1462-8910            Impact factor:   3.788


  17 in total

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4.  Management of Fistula-in-Ano-The Current Evidence.

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5.  Anal fistula closure with FiLaC: new hope or the same old story?

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Review 7.  Biomaterials in the treatment of anal fistula: hope or hype?

Authors:  Daniele Scoglio; Avery S Walker; Alessandro Fichera
Journal:  Clin Colon Rectal Surg       Date:  2014-12

Review 8.  Treatments for the amelioration of persistent factors in complex anal fistula.

Authors:  Daniel P Fitzpatrick; Carmel Kealey; Damien Brady; Martin Goodman; Noel Gately
Journal:  Biotechnol Lett       Date:  2021-11-19       Impact factor: 2.461

9.  Prospective evaluation of a new device for the treatment of anal fistulas.

Authors:  Carlo Ratto; Francesco Litta; Lorenza Donisi; Angelo Parello
Journal:  World J Gastroenterol       Date:  2016-08-14       Impact factor: 5.742

10.  The use of Gore Bio-A in the management of the open abdomen.

Authors:  Paul Anthony Sutton; Jonathan Paul Evans; Sheik Uzair; Joseph V Varghese
Journal:  BMJ Case Rep       Date:  2013-02-25
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