Literature DB >> 22288043

Mediastinal mature teratoma in a Jehovah's Witness: Discrepancy between imaging and intraoperative findings.

Farzaneh Banki1, Ryan Schniederjan, Wei Feng, Larry R Kaiser.   

Abstract

INTRODUCTION: Primary mediastinal germ cell tumors are exceedingly rare but may present with a wide spectrum of elements. The occasional mediastinal teratoma that presents completely comprised of mature elements is a benign tumor but the appearance on imaging studies may be more suggestive of an invasive tumor. The treatment is complete resection but the assessment of resectability based on computed tomographic imaging can be misleading. PRESENTATION OF CASE: We present a case of a 26 year old female, Jehovah's Witness who presented with a symptomatic mediastinal mass that on CT scan appeared to be unresectable due to presumed invasion of adjacent structures including the left pulmonary artery. Surgical exploration revealed an encapsulated, completely resectable mass which was excised without difficulty. Her early postoperative course was uneventful and at 18 months follow up is doing well without evidence of recurrence. DISCUSSION: The treatment of mature teratoma is complete surgical excision but the imaging studies may at times be misleading. We believe this case presents a unique clinical situation, since mediastinal mature teratomas are very rare and in addition, the preoperative decision to excise a mass becomes more complex in a case of a Jehovah's Witness. This case illustrates that the CT findings may be misleading when assessing a mediastinal mass.
CONCLUSION: Resectability of a mediastinal mass can only be assessed at the time of operation and rarely should operation be denied solely on the basis of findings on imaging. Thus in these primary mediastinal tumors there should be a low threshold for proceeding with operation.

Entities:  

Keywords:  Mature teratoma; Mediastinal mass

Year:  2011        PMID: 22288043      PMCID: PMC3267256          DOI: 10.1016/j.ijscr.2011.10.010

Source DB:  PubMed          Journal:  Int J Surg Case Rep        ISSN: 2210-2612


  5 in total

1.  Mediastinal mature teratoma: imaging features.

Authors:  K H Moeller; M L Rosado-de-Christenson; P A Templeton
Journal:  AJR Am J Roentgenol       Date:  1997-10       Impact factor: 3.959

2.  [Mature teratome of the mediastinum].

Authors:  M Smahi; A Achir; A Chafik; A S al Aziz; A el Messlout; A Benosman
Journal:  Ann Chir       Date:  2000-12

Review 3.  The primary mediastinal growing teratoma syndrome.

Authors:  A Iyoda; K Hiroshima; T Yusa; T Toyozaki; T Fujisawa; H Ohwada
Journal:  Anticancer Res       Date:  2000 Sep-Oct       Impact factor: 2.480

4.  Massive immature mediastinal teratoma extending into the left pleural cavity.

Authors:  Nicholas P McLeod; Michael P Vallely; Manu N Mathur
Journal:  Heart Lung Circ       Date:  2004-12-21       Impact factor: 2.975

5.  Germ cell tumors of the mediastinum. A 30-year experience.

Authors:  E M Dulmet; P Macchiarini; B Suc; J M Verley
Journal:  Cancer       Date:  1993-09-15       Impact factor: 6.860

  5 in total

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