Literature DB >> 22287748

Pelvic dysfunctions and quality of life after nerve-sparing radical hysterectomy: a multicenter comparative study.

Marcello Ceccaroni1, Giovanni Roviglione, Emanuela Spagnolo, Paolo Casadio, Roberto Clarizia, Michele Peiretti, Francesco Bruni, Inge Peters, Giovanni Aletti.   

Abstract

AIM: To analyze pelvic dysfunctions, quality of life, and survival after nerve-sparing radical hysterectomy (NSRH) compared to classical radical hysterectomy (RH) for cervical cancer. PATIENTS AND METHODS: All cervical cancer patients undergoing a RH or a NSRH were evaluated for pelvic dysfunctions and filled in a quality-of-life questionnaire.
RESULTS: A total of 56 women were included; 31 underwent RH (group 1) and 25 NSRH (group 2). Postoperatively, a higher number of patients had urinary incontinence (p=0.02), urinary retention (p=0.01), faecal incontinence (p=0.01) and constipation (p=0.01) in group 1 versus group 2. Patients referred a higher rate of severe sexual dysfunction after RH compared to NSRH (p=0.03). No differences were found in orgasmic frequency and sexual desire; overall quality of life evaluation was more satisfactory after NSRH.
CONCLUSION: NSRH conferred a better clinical outcome with fewer long-term bladder, colorectal and sexual complications. Post-operative quality of life after NSRH was better, with the same overall survival as compared to RH.

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Mesh:

Year:  2012        PMID: 22287748

Source DB:  PubMed          Journal:  Anticancer Res        ISSN: 0250-7005            Impact factor:   2.480


  15 in total

Review 1.  Nerve-sparing radical hysterectomy compared to standard radical hysterectomy for women with early stage cervical cancer (stage Ia2 to IIa).

Authors:  Chumnan Kietpeerakool; Apiwat Aue-Aungkul; Khadra Galaal; Chetta Ngamjarus; Pisake Lumbiganon
Journal:  Cochrane Database Syst Rev       Date:  2019-02-12

Review 2.  Lower urinary tract dysfunction after nerve-sparing radical hysterectomy.

Authors:  Fouad Aoun; Roland van Velthoven
Journal:  Int Urogynecol J       Date:  2014-11-29       Impact factor: 2.894

Review 3.  Pelvic floor disorders in women with gynecologic malignancies: a systematic review.

Authors:  Aparna S Ramaseshan; Jessica Felton; Dana Roque; Gautam Rao; Andrea G Shipper; Tatiana V D Sanses
Journal:  Int Urogynecol J       Date:  2017-09-19       Impact factor: 2.894

4.  Total laparoscopic bladder resection in the management of deep endometriosis: "take it or leave it." Radicality versus persistence.

Authors:  Marcello Ceccaroni; Roberto Clarizia; Matteo Ceccarello; Paola De Mitri; Giovanni Roviglione; Daniele Mautone; Giuseppe Caleffi; Alberto Molinari; Giacomo Ruffo; Stefano Cavalleri
Journal:  Int Urogynecol J       Date:  2019-09-07       Impact factor: 2.894

Review 5.  Maintaining sexual health throughout gynecologic cancer survivorship: A comprehensive review and clinical guide.

Authors:  Laura B Huffman; Ellen M Hartenbach; Jeanne Carter; Joanne K Rash; David M Kushner
Journal:  Gynecol Oncol       Date:  2015-11-07       Impact factor: 5.482

6.  Conventional versus nerve-sparing radical surgery for cervical cancer: a meta-analysis.

Authors:  Hee Seung Kim; Keewon Kim; Seung Bum Ryoo; Joung Hwa Seo; Sang Youn Kim; Ji Won Park; Min A Kim; Kyoung Sup Hong; Chang Wook Jeong; Yong Sang Song
Journal:  J Gynecol Oncol       Date:  2015-04       Impact factor: 4.401

7.  Quality of life and sexuality in disease-free survivors of cervical cancer after radical hysterectomy alone: A comparison between total laparoscopy and laparotomy.

Authors:  Meizhu Xiao; Huiqiao Gao; Huimin Bai; Zhenyu Zhang
Journal:  Medicine (Baltimore)       Date:  2016-09       Impact factor: 1.889

8.  Functional and molecular changes of the bladder in rats with crushing injury of nerve bundles from major pelvic ganglion to the bladder: role of RhoA/Rho kinase pathway.

Authors:  Su Jin Kim; Dong Sup Lee; Woong Jin Bae; Seol Kim; Sung Hoo Hong; Ji Youl Lee; Tae-Kon Hwang; Sae Woong Kim
Journal:  Int J Mol Sci       Date:  2013-08-27       Impact factor: 5.923

Review 9.  Clinical efficacy and safety of nerve-sparing radical hysterectomy for cervical cancer: a systematic review and meta-analysis.

Authors:  Ying Long; De-Sheng Yao; Xin-Wei Pan; Ting-Yu Ou
Journal:  PLoS One       Date:  2014-04-18       Impact factor: 3.240

Review 10.  Emotional and sexual concerns in women undergoing pelvic surgery and associated treatment for gynecologic cancer.

Authors:  Cara Stabile; Abigail Gunn; Yukio Sonoda; Jeanne Carter
Journal:  Transl Androl Urol       Date:  2015-04
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