| Literature DB >> 22286359 |
Abstract
Multiple myeloma (MM) is a disease of the elderly with an incidence of 4/100,000 per year and can occur as a comorbidity especially in elderly patients with rheumatoid arthritis (RA). For MM and also for RA interleukin-6 (IL-6) is a pathogenetically important cytokine in both disease events. This article presents the case of a female patient who achieved sustained remission of RA and stabilization of MM with quantitative reduction of paraprotein by treatment with tocilizumab. The question whether tocilizumab represents a meaningful treatment approach for treatment of RA when MM is also present will be discussed.Entities:
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Year: 2012 PMID: 22286359 DOI: 10.1007/s00393-011-0931-2
Source DB: PubMed Journal: Z Rheumatol ISSN: 0340-1855 Impact factor: 1.372