Literature DB >> 22285327

Implementation of a comprehensive blood conservation program can reduce blood use in a community cardiac surgery program.

Steve Xydas1, Christopher J Magovern, James P Slater, John M Brown, Rami Bustami, Grant V Parr, Robert L Thurer.   

Abstract

OBJECTIVE: The study objective was to determine the effects of implementing a blood conservation algorithm on blood product use and outcomes in a community cardiac surgery program.
METHODS: A blood management strategy including lower hemoglobin transfusion threshold and algorithm-driven decisions was adopted. Intraoperatively, point-of-care testing was used to avoid inappropriate component transfusion. A low prime perfusion circuit was adopted. Blood was withdrawn from patients before initiating bypass when possible. Patients undergoing coronary and valve procedures were included. Outlier patients receiving more than 10 units packed red blood cells were excluded. Data were collected for 6 months as a baseline group (group I). A 3-month period of program implementation was allotted. Data were subsequently collected for 6 months and comprised the study patients (group II). Prospective data were collected on demographics, blood use, and outcomes.
RESULTS: Group I comprised 481 patients, and group II comprised 551 patients. Group II received fewer units of packed red blood cells, fresh-frozen plasma, and cryoprecipitate than group I. There was no difference in platelets transfused. Total blood product use was reduced by 40% in group II (P < .001). The overall 30-day mortality was 1.3%. There were no differences in mortality, reoperation for bleeding, or other postoperative outcomes between the groups.
CONCLUSIONS: Implementation of a comprehensive blood conservation algorithm can be rapidly introduced, leading to reductions in blood and component use with no detrimental effect on early outcomes. Point-of-care testing can direct component transfusion in coagulopathic cases, with most coagulopathic patients requiring platelets. Further research will determine the effects of reduced transfusions on long-term outcomes. Copyright Â
© 2012 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.

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Year:  2012        PMID: 22285327     DOI: 10.1016/j.jtcvs.2012.01.003

Source DB:  PubMed          Journal:  J Thorac Cardiovasc Surg        ISSN: 0022-5223            Impact factor:   5.209


  4 in total

1.  The Influence of Intraoperative Autotransfusion on Postoperative Hematocrit after Cardiac Surgery: A Cross-Sectional Study.

Authors:  Andrew J Stasko; Alfred H Stammers; Linda B Mongero; Eric A Tesdahl; Samuel Weinstein
Journal:  J Extra Corpor Technol       Date:  2017-12

2.  Supplemental findings from the National Blood Collection and Utilization Surveys, 2013 and 2015.

Authors:  Mathew R P Sapiano; Alexandra A Savinkina; Katherine D Ellingson; Kathryn A Haass; Misha L Baker; Richard A Henry; James J Berger; Matthew J Kuehnert; Sridhar V Basavaraju
Journal:  Transfusion       Date:  2017-06       Impact factor: 3.157

3.  Continued decline in blood collection and transfusion in the United States-2015.

Authors:  Katherine D Ellingson; Mathew R P Sapiano; Kathryn A Haass; Alexandra A Savinkina; Misha L Baker; Koo-Whang Chung; Richard A Henry; James J Berger; Matthew J Kuehnert; Sridhar V Basavaraju
Journal:  Transfusion       Date:  2017-06       Impact factor: 3.157

4.  Blood conservation strategies in cardiac valve replacement: A retrospective analysis of 1645 patients.

Authors:  Junnan Zheng; Liangwei Chen; Linfeng Qian; Jianjie Jiang; Yinglian Chen; Jue Xie; Liping Shi; Yiming Ni; Haige Zhao
Journal:  Medicine (Baltimore)       Date:  2016-10       Impact factor: 1.889

  4 in total

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