Literature DB >> 2228428

Trypanosoma cruzi: calcium ion movement during internalization in host HeLa cells.

A Osuna1, S Castanys, M N Rodriguez-Cabezas, F Gamarro.   

Abstract

The role of cytosolic Ca2+ and cytoplasmic calcium movement during the parasitization of HeLa cells by T. cruzi were studied. The level of calcium in parasitized cells increased compared to the control cells. Our experiments demonstrate that this cytosolic calcium originates from the release of the intracellular calcium deposits, especially from the mitochondria of the host cell. The parasitization rates decreased after the cells were treated with drugs to increase the cytosolic Ca2+ levels to inhibit the host-cell calmodulin.

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Year:  1990        PMID： 2228428     DOI： 10.1016/0020-7519(90)90126-8

Source DB:  PubMed          Journal:  Int J Parasitol        ISSN： 0020-7519            Impact factor:   3.981


  5 in total

1.  Differential expression and characterization of a member of the mucin-associated surface protein family secreted by Trypanosoma cruzi.

Authors:  Luis Miguel De Pablos; Gloria González González; Jennifer Solano Parada; Víctor Seco Hidalgo; Isabel María Díaz Lozano; María Mercedes Gómez Samblás; Teresa Cruz Bustos; Antonio Osuna
Journal:  Infect Immun       Date:  2011-07-25       Impact factor: 3.441

2.  Conserved regions as markers of different patterns of expression and distribution of the mucin-associated surface proteins of Trypanosoma cruzi.

Authors:  Luis M De Pablos; Antonio Osuna
Journal:  Infect Immun       Date:  2011-10-24       Impact factor: 3.441

3.  Insight into the Exoproteome of the Tissue-Derived Trypomastigote form of Trypanosoma cruzi.

Authors:  Rayner M L Queiroz; Carlos A O Ricart; Mara O Machado; Izabela M D Bastos; Jaime M de Santana; Marcelo V de Sousa; Peter Roepstorff; Sébastien Charneau
Journal:  Front Chem       Date:  2016-11-07       Impact factor: 5.221

4.  Cytosolic-free calcium elevation in Trypanosoma cruzi is required for cell invasion.

Authors:  S N Moreno; J Silva; A E Vercesi; R Docampo
Journal:  J Exp Med       Date:  1994-10-01       Impact factor: 14.307

Review 5.  Mammalian cellular culture models of Trypanosoma cruzi infection: a review of the published literature.

Authors:  Gabriel Alberto Duran-Rehbein; Juan Camilo Vargas-Zambrano; Adriana Cuéllar; Concepción Judith Puerta; John Mario Gonzalez
Journal:  Parasite       Date:  2014-08-04       Impact factor: 3.000
  5 in total

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