Literature DB >> 22282924

The differential effects of flumazenil on the psychomotor and amnesic actions of midazolam.

B Birch1, H V Curran.   

Abstract

Forty-four patients given midazolam prior to day-care urological surgery had the benzodiazepine antagonist, flumazenil, or placebo administered postoperatively. Flumazenil reversed the psychomotor impairments induced by midazolam but not its amnesic effects. There was no evidence of resedation for up to 6 h following the use of flumazenil.

Entities:  

Year:  1990        PMID: 22282924     DOI: 10.1177/026988119000400105

Source DB:  PubMed          Journal:  J Psychopharmacol        ISSN: 0269-8811            Impact factor:   4.153


  10 in total

1.  A comparison of the effects of scopolamine and diazepam on working memory.

Authors:  J M Rusted; P Eaton-Williams; D M Warburton
Journal:  Psychopharmacology (Berl)       Date:  1991       Impact factor: 4.530

2.  Bidirectional effects of benzodiazepine binding site ligands on active avoidance acquisition and retention: differential antagonism by flumazenil and beta-CCt.

Authors:  Miroslav M Savić; Dragan I Obradović; Nenad D Ugresić; James M Cook; P V V S Sarma; Dubravko R Bokonjić
Journal:  Psychopharmacology (Berl)       Date:  2005-02-18       Impact factor: 4.530

Review 3.  Cognition enhancers in age-related cognitive decline.

Authors:  W J Riedel; J Jolles
Journal:  Drugs Aging       Date:  1996-04       Impact factor: 3.923

Review 4.  Benzodiazepines, memory and mood: a review.

Authors:  H V Curran
Journal:  Psychopharmacology (Berl)       Date:  1991       Impact factor: 4.530

5.  Differentiating the sedative, psychomotor and amnesic effects of benzodiazepines: a study with midazolam and the benzodiazepine antagonist, flumazenil.

Authors:  H V Curran; B Birch
Journal:  Psychopharmacology (Berl)       Date:  1991       Impact factor: 4.530

6.  Dissociation of benzodiazepine-induced amnesia from sedation by flumazenil pretreatment.

Authors:  D Hommer; H Weingartner; A Breier
Journal:  Psychopharmacology (Berl)       Date:  1993       Impact factor: 4.530

7.  The cognitive and psychomotor effects of opioid analgesics. I. A randomized controlled trial of single doses of dextropropoxyphene, lorazepam and placebo in healthy subjects.

Authors:  W M O'Neill; G W Hanks; L White; P Simpson; K Wesnes
Journal:  Eur J Clin Pharmacol       Date:  1995       Impact factor: 2.953

8.  An effect of triazolam on visual attention and information processing.

Authors:  D N Johnson; H J Weingartner; P Andreason; D T George
Journal:  Psychopharmacology (Berl)       Date:  1995-09       Impact factor: 4.530

9.  Psychopharmacological analysis of implicit and explicit memory: a study with lorazepam and the benzodiazepine antagonist flumazenil.

Authors:  K I Bishop; H V Curran
Journal:  Psychopharmacology (Berl)       Date:  1995-09       Impact factor: 4.530

10.  The value of assessing cognitive function in drug development.

Authors:  K A Wesnes
Journal:  Dialogues Clin Neurosci       Date:  2000-09       Impact factor: 5.986

  10 in total

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