Literature DB >> 22279043

Wnt signaling: the β-cat(enin)'s meow.

Matthieu Bauer1, Karl Willert.   

Abstract

In a study in the December 15, 2011, issue of Genes & Development, Valenta and colleagues (pp. 2631-2643) constructed a series of β-catenin mutants that allowed them to separate β-catenin's activity as a mediator of Wnt signaling from its activity as cell adhesion component. In doing so, they uncovered some surprising properties of Wnt signaling.

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Year:  2012        PMID： 22279043      PMCID： PMC3273833          DOI： 10.1101/gad.185280.111

Source DB:  PubMed          Journal:  Genes Dev        ISSN： 0890-9369            Impact factor:   11.361


  21 in total

1.  Functional characterization of multiple transactivating elements in beta-catenin, some of which interact with the TATA-binding protein in vitro.

Authors:  A Hecht; C M Litterst; O Huber; R Kemler
Journal:  J Biol Chem       Date:  1999-06-18       Impact factor: 5.157

2.  Wingless signaling modulates cadherin-mediated cell adhesion in Drosophila imaginal disc cells.

Authors:  Andreas Wodarz; Daniel B Stewart; W James Nelson; Roel Nusse
Journal:  J Cell Sci       Date:  2006-05-23       Impact factor: 5.285

3.  XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos.

Authors:  M Molenaar; M van de Wetering; M Oosterwegel; J Peterson-Maduro; S Godsave; V Korinek; J Roose; O Destrée; H Clevers
Journal:  Cell       Date:  1996-08-09       Impact factor: 41.582

4.  Three-dimensional structure of the armadillo repeat region of beta-catenin.

Authors:  A H Huber; W J Nelson; W I Weis
Journal:  Cell       Date:  1997-09-05       Impact factor: 41.582

5.  The C-terminal transactivation domain of beta-catenin is necessary and sufficient for signaling by the LEF-1/beta-catenin complex in Xenopus laevis.

Authors:  K Vleminckx; R Kemler; A Hecht
Journal:  Mech Dev       Date:  1999-03       Impact factor: 1.882

6.  Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase.

Authors:  P S Danielian; D Muccino; D H Rowitch; S K Michael; A P McMahon
Journal:  Curr Biol       Date:  1998-12-03       Impact factor: 10.834

7.  Pygopus, a nuclear PHD-finger protein required for Wingless signaling in Drosophila.

Authors:  David S Parker; Jemileh Jemison; Kenneth M Cadigan
Journal:  Development       Date:  2002-06       Impact factor: 6.868

8.  Mapping Wnt/beta-catenin signaling during mouse development and in colorectal tumors.

Authors:  Silvia Maretto; Michelangelo Cordenonsi; Sirio Dupont; Paola Braghetta; Vania Broccoli; A Bassim Hassan; Dino Volpin; Giorgio M Bressan; Stefano Piccolo
Journal:  Proc Natl Acad Sci U S A       Date:  2003-03-07       Impact factor: 11.205

9.  An in vivo structure-function study of armadillo, the beta-catenin homologue, reveals both separate and overlapping regions of the protein required for cell adhesion and for wingless signaling.

Authors:  S Orsulic; M Peifer
Journal:  J Cell Biol       Date:  1996-09       Impact factor: 10.539

10.  Lack of beta-catenin affects mouse development at gastrulation.

Authors:  H Haegel; L Larue; M Ohsugi; L Fedorov; K Herrenknecht; R Kemler
Journal:  Development       Date:  1995-11       Impact factor: 6.868
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  3 in total

1.  Folic Acid Protects Against Glutamate-Induced Excitotoxicity in Hippocampal Slices Through a Mechanism that Implicates Inhibition of GSK-3β and iNOS.

Authors:  Josiane Budni; Simone Molz; Tharine Dal-Cim; Maria Dolores Martín-de-Saavedra; Javier Egea; Manuela G Lopéz; Carla Ines Tasca; Ana Lúcia Severo Rodrigues
Journal:  Mol Neurobiol       Date:  2017-02-10       Impact factor: 5.590

2.  Inhibition of GSK3α/β promotes increased pulmonary endothelial permeability to albumin by reactive oxygen/nitrogen species.

Authors:  Paul Neumann; Hiba Alsaffar; Nancy Gertzberg; Arnold Johnson
Journal:  Pulm Pharmacol Ther       Date:  2013-06-11       Impact factor: 3.410

3.  Salvianolic acid B regulates gene expression and promotes cell viability in chondrocytes.

Authors:  Xiaohong Yang; Shaojie Liu; Siming Li; Pengzhen Wang; Weicong Zhu; Peihong Liang; Jianrong Tan; Shuliang Cui
Journal:  J Cell Mol Med       Date:  2017-02-28       Impact factor: 5.310
  3 in total

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