Literature DB >> 22277060

Ultraviolet A1 phototherapy: a British Photodermatology Group workshop report.

A C Kerr1, J Ferguson, S K Attili, P E Beattie, A J Coleman, R S Dawe, B Eberlein, V Goulden, S H Ibbotson, H du P Menage, H Moseley, L Novakovic, S L Walker, J A Woods, A R Young, R P E Sarkany.   

Abstract

Whole-body ultraviolet (UV)A1 (340-400 nm) phototherapy was first introduced 30 years ago, but is currently available in the UK in only three dermatology departments. A workshop to discuss UVA1 was held by the British Photodermatology Group in May 2009, the aim of which was to provide an overview of UVA1 phototherapy and its role in practice, and to identify areas in which further studies are required. The conclusions were that UVA1 phototherapy is an effective treatment in several inflammatory skin diseases, including localized scleroderma and atopic eczema (AE); however, deficiencies and limitations exist in the published evidence base. For most diseases, such as AE, other treatments also exist, which are generally more effective than UVA1. However, for some diseases, particularly morphoea, the evidence of efficacy is stronger for UVA1 than for other treatments. Acute adverse effects of UVA1 are minimal. The risk of long-term adverse effects, particularly skin cancer, is unknown. Medium to high doses of UVA1 are needed for efficacy in most situations, but the equipment to deliver such doses is large, expensive and difficult to install. UVA1 is currently underprovided, and the recommendation of the workshop is that more tertiary centres should have access to UVA1 phototherapy in the UK. © The Author(s). CED
© 2012 British Association of Dermatologists.

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Year:  2012        PMID: 22277060     DOI: 10.1111/j.1365-2230.2011.04256.x

Source DB:  PubMed          Journal:  Clin Exp Dermatol        ISSN: 0307-6938            Impact factor:   3.470


  9 in total

1.  Upregulation of MMP12 and its activity by UVA1 in human skin: potential implications for photoaging.

Authors:  Angela Tewari; Katarzyna Grys; Jutta Kollet; Robert Sarkany; Antony R Young
Journal:  J Invest Dermatol       Date:  2014-04-08       Impact factor: 8.551

2.  UVA1 a promising approach for scleroderma.

Authors:  Uma Keyal; Anil Kumar Bhatta; Xiu Li Wang
Journal:  Am J Transl Res       Date:  2017-09-15       Impact factor: 4.060

Review 3.  The role of dendritic cells and regulatory T cells in the pathogenesis of morphea.

Authors:  Agnieszka Osmola-Mańkowska; Ewa Teresiak-Mikołajczak; Aleksandra Dańczak-Pazdrowska; Michał Kowalczyk; Ryszard Żaba; Zygmunt Adamski
Journal:  Cent Eur J Immunol       Date:  2015-04-22       Impact factor: 2.085

4.  Diversity of biological effects induced by longwave UVA rays (UVA1) in reconstructed skin.

Authors:  Claire Marionnet; Cécile Pierrard; Christelle Golebiewski; Françoise Bernerd
Journal:  PLoS One       Date:  2014-08-20       Impact factor: 3.240

Review 5.  Ultraviolet A1 Phototherapy for Fibrosing Conditions.

Authors:  Thilo Gambichler; Lutz Schmitz
Journal:  Front Med (Lausanne)       Date:  2018-08-27

6.  Sunscreens with the New MCE Filter Cover the Whole UV Spectrum: Improved UVA1 Photoprotection In Vitro and in a Randomized Controlled Trial.

Authors:  Claire Marionnet; Romain de Dormael; Xavier Marat; Angélina Roudot; Julie Gizard; Emilie Planel; Carine Tornier; Christelle Golebiewski; Philippe Bastien; Didier Candau; Françoise Bernerd
Journal:  JID Innov       Date:  2021-11-25

Review 7.  The Damaging Effects of Long UVA (UVA1) Rays: A Major Challenge to Preserve Skin Health and Integrity.

Authors:  Françoise Bernerd; Thierry Passeron; Isabelle Castiel; Claire Marionnet
Journal:  Int J Mol Sci       Date:  2022-07-26       Impact factor: 6.208

8.  Protection of the biconcave profile of human erythrocytes against osmotic damage by ultraviolet-A irradiation through membrane-cytoskeleton enhancement.

Authors:  Cunbo Li; Zheming Li; Shuang Xun; Pengchong Jiang; Rui Yan; Mincai Chen; Fen Hu; Romano A Rupp; Xinzheng Zhang; Leiting Pan; Jingjun Xu
Journal:  Cell Death Discov       Date:  2017-07-17

9.  The UV/Visible Radiation Boundary Region (385-405 nm) Damages Skin Cells and Induces "dark" Cyclobutane Pyrimidine Dimers in Human Skin in vivo.

Authors:  Karl P Lawrence; Thierry Douki; Robert P E Sarkany; Stephanie Acker; Bernd Herzog; Antony R Young
Journal:  Sci Rep       Date:  2018-08-24       Impact factor: 4.379

  9 in total

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