Literature DB >> 22273378

Antitumor cyclic hexapeptides from rubia plants: history, chemistry, and mechanism (2005-2011).

Si Meng Zhao1, Bin Kuang, Jun Ting Fan, He Yan, Wen Yan Xu, Ning Hua Tan.   

Abstract

Rubiaceae-type cyclopeptides (RAs), cyclic hexapeptides from Rubia plants, have shown potential antitumor activity in vitro and in vivo. Based on the review about plant cyclopeptides (Chem. Rev., 2006, 106: 840), this mini-review will highlight new progress on the discovery, synthesis, and mechanism of RAs isolated during 2005 to 2011, covering recent work in our group.

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Year:  2011        PMID: 22273378     DOI: 10.2533/chimia.2011.952

Source DB:  PubMed          Journal:  Chimia (Aarau)        ISSN: 0009-4293            Impact factor:   1.509


  5 in total

1.  Rubipodanin A, the First Natural N-Desmonomethyl Rubiaceae-Type Cyclopeptide from Rubia podantha, Indicating an Important Role of the N9-Methyl Group in the Conformation and Bioactivity.

Authors:  Zhe Wang; Si-Meng Zhao; Li-Mei Zhao; Xiao-Qiang Chen; Guang-Zhi Zeng; Ning-Hua Tan
Journal:  PLoS One       Date:  2015-12-22       Impact factor: 3.240

2.  Natural cyclopeptide RA-V inhibits the NF-κB signaling pathway by targeting TAK1.

Authors:  Zhe Wang; Simeng Zhao; Lihua Song; Yuzhi Pu; Qiang Wang; Guangzhi Zeng; Xing Liu; Ming Bai; Shao Li; Fabao Gao; Lijuan Chen; Chen Wang; Ninghua Tan
Journal:  Cell Death Dis       Date:  2018-06-18       Impact factor: 8.469

3.  Crosstalk of Cancer Signaling Pathways by Cyclic Hexapeptides and Anthraquinones from Rubia cordifolia.

Authors:  Premalatha Balachandran; Mohamed Ali Ibrahim; Jin Zhang; Mei Wang; David S Pasco; Ilias Muhammad
Journal:  Molecules       Date:  2021-01-31       Impact factor: 4.411

4.  Rubia tinctorum root extracts: chemical profile and management of type II diabetes mellitus.

Authors:  Enas E Eltamany; Mohamed S Nafie; Dina M Khodeer; Aya H H El-Tanahy; Maged S Abdel-Kader; Jihan M Badr; Reda F A Abdelhameed
Journal:  RSC Adv       Date:  2020-06-24       Impact factor: 4.036

5.  Structural and bioactive studies of terpenes and cyclopeptides from the Genus Rubia.

Authors:  Kuo Xu; Penglong Wang; Bin Yuan; Yatao Cheng; Qiang Li; Haimin Lei
Journal:  Chem Cent J       Date:  2013-05-04       Impact factor: 4.215

  5 in total

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