Literature DB >> 22273222

Breast cancer reconstruction in the elderly.

Marissa Howard-McNatt1, Clay Forsberg, Edward A Levine, Anthony DeFranzo, Malcolm Marks, Lisa David.   

Abstract

Mastectomy is a surgical choice for breast cancer, yet breast reconstruction is underused in women older than age 60 years. Because of a paucity of information examining breast cancer reconstruction in the elderly, we sought to review our experience. By retrospective chart review, we evaluated 89 women older than 60 years having mastectomy and reconstruction from January 1998 to June 2008. Mean patient age was 65 years (range, 60 to 74 years). The majority (41%) had Stage 1 disease or Stage 2 (30%). Ductal carcinoma in situ comprised 25 per cent and Stage 3 totaled 2 per cent. Mastectomy for ipsilateral breast tumor recurrence after radiation therapy and lumpectomy comprised 11 per cent. Most underwent immediate breast reconstruction (89%). Reconstructive techniques included two-stage implant (58%), transverse rectus abdominus musculocutaneous (TRAM) flap (10%), latissimus dorsi musculocutaneous flap with implant (2%), or deep inferior epigastric perforator flap (1%). Complications included a 12 per cent infection rate, removal of two expanders resulting from exposure, one TRAM failure, and one TRAM required débriding. Four patients undergoing mastectomy with tissue expander had radiation resulting in one expander being removed. One local skin recurrence was treated with removal of implant and skin resection. Two patients have died from metastatic disease. Age should not be a contraindication for breast reconstruction in elderly women.

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Mesh:

Year:  2011        PMID: 22273222

Source DB:  PubMed          Journal:  Am Surg        ISSN: 0003-1348            Impact factor:   0.688


  5 in total

1.  Factors influencing the decision to pursue immediate breast reconstruction after mastectomy for breast cancer.

Authors:  Mariska Weenk; Philipp Wunschel; Erwin Heine; Luc J Strobbe
Journal:  Gland Surg       Date:  2017-02

2.  Multidisciplinary approach to breast angiosarcoma in an elderly patient: Repeated local relapses and significant objective responses.

Authors:  Carmela Mocerino; Giuseppe Iannaci; Patrizia Sapere; Rossella Luise; Silvestro Canonico; Antonio Gambardella
Journal:  Int J Immunopathol Pharmacol       Date:  2016-02-12       Impact factor: 3.219

Review 3.  Patients opting for breast reconstruction following mastectomy: an analysis of uptake rates and benefit.

Authors:  Marissa M Howard-McNatt
Journal:  Breast Cancer (Dove Med Press)       Date:  2013-02-25

Review 4.  Outcomes in Deep Inferior Epigastric Perforator Flap and Implant-Based Reconstruction: Does Age Really Matter?

Authors:  Lauren V Kuykendall; Angie Zhang; Bugra Tugertimur; Sara Bijan; Corin Agoris; Ambuj Kumar; Deniz Dayicioglu
Journal:  Cancer Control       Date:  2018 Jan-Mar       Impact factor: 3.302

5.  Immediate breast reconstruction for women having inflammatory breast cancer in the United States.

Authors:  Sameer A Patel; Marilyn Ng; Salvatore M Nardello; Karen Ruth; Richard J Bleicher
Journal:  Cancer Med       Date:  2018-05-15       Impact factor: 4.711

  5 in total

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