| Literature DB >> 22273027 |
W Lowman, C Sriruttan, T Nana, N Bosman, A Duse, J Venturas, C Clay, J Coetzee.
Abstract
The New Delhi Metallo-β-lactamase (NDM) resistance mechanism in Enterobacteriaceae threatens to render serious Gram-negative infections untreatable. The NDM-1 enzyme hydrolyses all available penicillin, cephalosporin and carbapenem antibiotics, and is commonly accompanied by additional resistance mechanisms to multiple antibiotic classes. Initially identified as a significant healthcare risk on the Indian sub-continent, it has rapidly become a global problem, posing significant diagnostic and management challenges. Here we report the first laboratory-confirmed case of NDM-1 in South Africa.Entities:
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Year: 2011 PMID： 22273027
Source DB: PubMed Journal: S Afr Med J