Literature DB >> 22269897

Phrynoderma: a rare dermatologic complication of bariatric surgery.

Julia Ocón1, Carmen Cabrejas, Jara Altemir, Manuel Moros.   

Abstract

Biliopancreatic diversion is a predominantly malabsorptive bariatric procedure that can lead to the development of several nutrition complications, including fat-soluble vitamin deficiencies. Routine supplementation with vitamins and trace elements and a strict medical follow-up are essential to prevent these nutrition risks. Vitamin A deficiency is common after bariatric surgery but rarely causes clinical symptoms. Case reports have described ophthalmological and fetal complications associated with vitamin A deficiency after malabsorptive bariatric surgery. Phrynoderma is a type of follicular hyperkeratosis located on the extensor surfaces of the extremities whose main cause is vitamin A deficiency. The simultaneous occurrence of phrynoderma and ocular symptoms secondary to hypovitaminosis A after bariatric surgery is exceptional. The authors describe a man who presented follicular hyperkeratosis with nyctalopia and xerophthalmia that had appeared 1 year after biliopancreatic diversion. He admitted poor compliance with diet and daily supplementation of vitamins and oligoelements. Serum vitamin A levels were decreased. Treatment with high doses of vitamin A was associated with a clear improvement of cutaneous and ocular lesions with complete resolution after 2 months. The patient was readmitted 2 years later because of the reappearance of cutaneous lesions and micronutrient deficiency. Revisional bariatric surgery was performed. The authors review and discuss the relationship between phrynoderma, malnutrition, and vitamin A deficiency.

Entities:  

Mesh:

Substances:

Year:  2012        PMID: 22269897     DOI: 10.1177/0148607111422067

Source DB:  PubMed          Journal:  JPEN J Parenter Enteral Nutr        ISSN: 0148-6071            Impact factor:   4.016


  5 in total

1.  Dietary vitamin A regulates wingless-related MMTV integration site signaling to alter the hair cycle.

Authors:  Liye Suo; John P Sundberg; Helen B Everts
Journal:  Exp Biol Med (Maywood)       Date:  2014-10-30

Review 2.  Bariatric surgery and its effects on the skin and skin diseases.

Authors:  Ali Halawi; Firass Abiad; Ossama Abbas
Journal:  Obes Surg       Date:  2013-03       Impact factor: 4.129

3.  Estrogen regulates the expression of retinoic acid synthesis enzymes and binding proteins in mouse skin.

Authors:  Helen B Everts; Kathleen A Silva; Adriana N Schmidt; Susan Opalenik; F Jason Duncan; Lloyd E King; John P Sundberg; David E Ong
Journal:  Nutr Res       Date:  2021-08-24       Impact factor: 3.876

Review 4.  Dermatological manifestations relating to nutritional deficiencies after bariatric surgery: case report and integrative literature review.

Authors:  Andressa Christine Ferreira Silva; Laura Moya Kazmarek; Elemir Macedo de Souza; Maria Letícia Cintra; Fernanda Teixeira
Journal:  Sao Paulo Med J       Date:  2022 Sep-Oct       Impact factor: 1.838

5.  Unusual manifestation of vitamin A deficiency presenting with generalized xerosis without night blindness.

Authors:  Pariya Phanachet; Prapimporn Chattranukulchai Shantavasinkul; Pichika Chantrathammachart; Ploysyne Rattanakaemakorn; Kulapong Jayanama; Surat Komindr; Daruneewan Warodomwichit
Journal:  Clin Case Rep       Date:  2018-03-13
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.