Literature DB >> 2226835

Importance of the G27-A43 mismatch at the anticodon stem of Escherichia coli tRNA(Thr2).

Y Komine1, H Inokuchi.   

Abstract

The tRNA(Thr2) isoacceptor of E. coli has a G-A mismatch at positions 27-43. When the anticodon of this tRNA was converted to an amber anticodon (CUA), this tRNA showed suppressor activity in E. coli. Moreover, introduction of the base pair (G-C or U-A) at positions 27-43 of this suppressor tRNA reduced its suppressor activity. These results indicate that the G27-A43 mismatch is necessary for full function of tRNA(Thr2).

Entities:  

Mesh：

Substances：

Year:  1990        PMID： 2226835     DOI： 10.1016/0014-5793(90)80447-q

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  4 in total

1.  Anticodon-dependent conservation of bacterial tRNA gene sequences.

Authors:  Margaret E Saks; John S Conery
Journal:  RNA       Date:  2007-03-22       Impact factor: 4.942

2.  The growth defect in Escherichia coli deficient in peptidyl-tRNA hydrolase is due to starvation for Lys-tRNA(Lys).

Authors:  V Heurgué-Hamard; L Mora; G Guarneros; R H Buckingham
Journal:  EMBO J       Date:  1996-06-03       Impact factor: 11.598

3.  The expression of E.coli threonyl-tRNA synthetase is regulated at the translational level by symmetrical operator-repressor interactions.

Authors:  P Romby; J Caillet; C Ebel; C Sacerdot; M Graffe; F Eyermann; C Brunel; H Moine; C Ehresmann; B Ehresmann; M Springer
Journal:  EMBO J       Date:  1996-11-01       Impact factor: 11.598

4.  Mutations in residues involved in zinc binding in the catalytic site of Escherichia coli threonyl-tRNA synthetase confer a dominant lethal phenotype.

Authors:  Joël Caillet; Monique Graffe; Flore Eyermann; Pascale Romby; Mathias Springer
Journal:  J Bacteriol       Date:  2007-07-20       Impact factor: 3.490
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.