Literature DB >> 22266982

A Seoul-Fluor-based bioprobe for lipid droplets and its application in image-based high throughput screening.

Eunha Kim1, Sanghee Lee, Seung Bum Park.   

Abstract

We developed a novel fluorescent bioprobe (SF44) that can specifically visualize the cellular lipid droplets in in vitro and in vivo systems and illustrated the mechanistic rationale of its fluorogenic property. Its application to image-based high throughput screening led us to the identification of a new small-molecule modulator of lipid droplet formation. This journal is © The Royal Society of Chemistry 2012

Entities:  

Mesh：

Substances：

Year:  2012        PMID： 22266982     DOI： 10.1039/c2cc17496k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  9 in total

1.  Intravital two-photon imaging and quantification of hepatic steatosis and fibrosis in a live small animal model.

Authors:  Jieun Moon; Jehwi Jeon; Eunji Kong; Sujung Hong; Jingu Lee; Eun Kyung Lee; Pilhan Kim
Journal:  Biomed Opt Express       Date:  2021-12-01       Impact factor: 3.732

2.  Rational perturbation of the fluorescence quantum yield in emission-tunable and predictable fluorophores (Seoul-Fluors) by a facile synthetic method involving C-H activation.

Authors:  Eun Joung Choi; Eunha Kim; Youngjun Lee; Ala Jo; Seung Bum Park
Journal:  Angew Chem Int Ed Engl       Date:  2014-01-20       Impact factor: 15.336

3.  Photoactivatable aggregation-induced emission probes for lipid droplets-specific live cell imaging.

Authors:  Meng Gao; Huifang Su; Yuhan Lin; Xia Ling; Shiwu Li; Anjun Qin; Ben Zhong Tang
Journal:  Chem Sci       Date:  2016-12-21       Impact factor: 9.825

4.  From Live Cells to Caenorhabditis elegans: Selective Staining and Quantification of Lipid Structures Using a Fluorescent Hybrid Benzothiadiazole Derivative.

Authors:  Alberto A R Mota; Jose R Correa; Lorena P de Andrade; José A F Assumpção; Giovana A de Souza Cintra; Lucio H Freitas-Junior; Wender A da Silva; Heibbe C B de Oliveira; Brenno A D Neto
Journal:  ACS Omega       Date:  2018-04-05

Review 5.  Recent Advances in Fluorescent Probes for Lipid Droplets.

Authors:  Tkhe Kyong Fam; Andrey S Klymchenko; Mayeul Collot
Journal:  Materials (Basel)       Date:  2018-09-18       Impact factor: 3.623

6.  Reactions of 5-Indolizyl Lithium Compounds with Some Bielectrophiles.

Authors:  Sergey A Rzhevskii; Victor B Rybakov; Victor N Khrustalev; Eugene V Babaev
Journal:  Molecules       Date:  2017-04-20       Impact factor: 4.411

7.  Intravital Two-photon Imaging of Dynamic Alteration of Hepatic Lipid Droplets in Fasted and Refed State.

Authors:  Jieun Moon; Pilhan Kim
Journal:  J Lipid Atheroscler       Date:  2021-06-28

Review 8.  Lipid Droplets in Cancer: From Composition and Role to Imaging and Therapeutics.

Authors:  Patrícia Antunes; Adriana Cruz; José Barbosa; Vasco D B Bonifácio; Sandra N Pinto
Journal:  Molecules       Date:  2022-02-01       Impact factor: 4.411

9.  Rational Improvement of Molar Absorptivity Guided by Oscillator Strength: A Case Study with Furoindolizine-Based Core Skeleton.

Authors:  Youngjun Lee; Ala Jo; Seung Bum Park
Journal:  Angew Chem Int Ed Engl       Date:  2015-11-13       Impact factor: 15.336
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.