Literature DB >> 22266649

Glycosylation assists binding of HIV protein gp120 to human CD4 receptor.

Dennis Wilhelm1, Henning N Behnken, Bernd Meyer.   

Abstract

The role of glycosylation of proteins on its binding affinity is not well understood. Even a monosaccharide (magenta) placed at a glycosylation site can significantly enhance binding of peptides to their receptor. If glycosylated, an HIV protein binds stronger and faster to its primary receptors on human cells.
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Mesh：

Substances：

Year:  2012        PMID： 22266649     DOI： 10.1002/cbic.201100740

Source DB:  PubMed          Journal:  Chembiochem        ISSN： 1439-4227            Impact factor:   3.164


  3 in total

Review 1.  Predicting the Structures of Glycans, Glycoproteins, and Their Complexes.

Authors:  Robert J Woods
Journal:  Chem Rev       Date:  2018-08-09       Impact factor: 60.622

2.  The Bipartite Sequence Motif in the N and C Termini of gp85 of Subgroup J Avian Leukosis Virus Plays a Crucial Role in Receptor Binding and Viral Entry.

Authors:  Yao Zhang; Mengmeng Yu; Lixiao Xing; Peng Liu; Yuntong Chen; Fangfang Chang; Suyan Wang; Yuanling Bao; Muhammad Farooque; Xinyi Li; Xiaolu Guan; Yongzhen Liu; Aijing Liu; Xiaole Qi; Qing Pan; Yanping Zhang; Li Gao; Kai Li; Changjun Liu; Hongyu Cui; Xiaomei Wang; Yulong Gao
Journal:  J Virol       Date:  2020-10-27       Impact factor: 5.103

3.  The influence of N-linked glycans on the molecular dynamics of the HIV-1 gp120 V3 loop.

Authors:  Natasha T Wood; Elisa Fadda; Robert Davis; Oliver C Grant; Joanne C Martin; Robert J Woods; Simon A Travers
Journal:  PLoS One       Date:  2013-11-26       Impact factor: 3.240
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.