Literature DB >> 22266264

Osteoarthritis year 2011 in review: clinical.

T E McAlindon1, J B Driban, G H Lo.   

Abstract

The purpose of this narrative year in review of clinical studies was to highlight a few publications related to obesity and weight loss, physical activity, and synovitis as well as disease modifying interventions that were published between September 2010 and September 2011. This year clinical research highlighted the extent to which obesity and osteoarthritis (OA) are impacting quality of life among adults in the United States and that reducing excessive body weight or becoming more physically active may be beneficial. In addition to weight loss and physical activity and synovitis, research over the past year has highlighted the diverse methods being pursued for structural modification interventions. In addition to chondroitin sulfate there were interesting preliminary findings that meniscal implants and joint distractions may modify OA progression. Copyright Â
© 2012. Published by Elsevier Ltd.

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Year:  2012        PMID: 22266264     DOI: 10.1016/j.joca.2011.12.015

Source DB:  PubMed          Journal:  Osteoarthritis Cartilage        ISSN: 1063-4584            Impact factor:   6.576


  3 in total

1.  Novel nano-microspheres containing chitosan, hyaluronic acid, and chondroitin sulfate deliver growth and differentiation factor-5 plasmid for osteoarthritis gene therapy.

Authors:  Zhu Chen; Shang Deng; De-Chao Yuan; Kang Liu; Xiao-Cong Xiang; Liang Cheng; Dong-Qin Xiao; Li Deng; Gang Feng
Journal:  J Zhejiang Univ Sci B       Date:  2018 Dec.       Impact factor: 3.066

Review 2.  Functional articular cartilage repair: here, near, or is the best approach not yet clear?

Authors:  Simon C Mastbergen; Daniël B F Saris; Floris P J G Lafeber
Journal:  Nat Rev Rheumatol       Date:  2013-03-19       Impact factor: 20.543

3.  Proprotein convertase furin inhibits matrix metalloproteinase 13 in a TGFβ-dependent manner and limits osteoarthritis in mice.

Authors:  Hilène Lin; Eric Hay; Augustin Latourte; Thomas Funck-Brentano; Wafa Bouaziz; Hang-Korng Ea; Abdel-Majid Khatib; Pascal Richette; Martine Cohen-Solal
Journal:  Sci Rep       Date:  2018-07-11       Impact factor: 4.379

  3 in total

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