| Literature DB >> 22265576 |
M Nowak1, A Strzelczyk, P S Reif, K Schorlemmer, S Bauer, B A Norwood, W H Oertel, F Rosenow, H Strik, H M Hamer.
Abstract
Minocycline, a tetracycline family antibiotic, is known to inhibit microglial activation and proinflammatory cytokine release in animal models. Experimental data show that these immune processes may play a role in epilepto- and ictogenesis. We present the case of a patient with marked reduction in seizure frequency during minocycline therapy with severe symptomatic epilepsy due to an astrocytoma. Copyright ÂEntities:
Mesh:
Substances:
Year: 2012 PMID: 22265576 DOI: 10.1016/j.seizure.2011.12.009
Source DB: PubMed Journal: Seizure ISSN: 1059-1311 Impact factor: 3.184