Literature DB >> 2226554

Variation of alpha 1-antitrypsin glycoprotein microheterogeneity in hepatic postresuscitation disease.

K Heyne1, F K Tegtmeyer, S Weidinger.   

Abstract

Microheterogeneity of the glycoprotein alpha 1-antitrypsin has been investigated sequentially by high resolution isoelectric focusing in a child with the proteinase inhibitor MS phenotype after near-drowning. A band-splitting with additional cathodal fractions exhibited migration from the most cathodic to the anodic positions of the glycoprotein isoforms in the course of post-resuscitation disease. The pattern may reflect the time- and stage-dependent hypoxic and post-hypoxic effects on hepatocellular metabolic zonation.

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Year:  1990        PMID： 2226554     DOI： 10.1007/bf01957283

Source DB:  PubMed          Journal:  Eur J Pediatr        ISSN： 0340-6199            Impact factor:   3.183


  17 in total

1.  Glycogen storage disease Ib: modification of alpha 1-antitrypsin glycoprotein microheterogeneity.

Authors:  K Heyne; J Henke-Wolter
Journal:  Eur J Pediatr       Date:  1989-01       Impact factor: 3.183

Review 2.  Biochemistry of reoxygenation injury.

Authors:  L Ernster
Journal:  Crit Care Med       Date:  1988-10       Impact factor: 7.598

3.  Hemorrhagic shock and encephalopathy: clinical, pathologic, and biochemical features.

Authors:  M Levin; J R Pincott; M Hjelm; F Taylor; J Kay; H Holzel; R Dinwiddie; D J Matthew
Journal:  J Pediatr       Date:  1989-02       Impact factor: 4.406

4.  Ischemic hepatitis in children: diagnosis and clinical course.

Authors:  J S Garland; S L Werlin; T B Rice
Journal:  Crit Care Med       Date:  1988-12       Impact factor: 7.598

Review 5.  Functional implications of liver cell heterogeneity.

Authors:  J J Gumucio; D L Miller
Journal:  Gastroenterology       Date:  1981-02       Impact factor: 22.682

6.  Glycogen synthesis from pyruvate in the periportal and from glucose in the perivenous zone in perfused livers from fasted rats.

Authors:  H Bartels; B Vogt; K Jungermann
Journal:  FEBS Lett       Date:  1987-09-14       Impact factor: 4.124

7.  D-galactosamine-induced liver injury: a rat model to study the heterogeneity of the oligosaccharide chains of alpha 1-acid glycoprotein.

Authors:  D Monnet; D Durand; D Biou; J Féger; G Durand
Journal:  J Clin Chem Clin Biochem       Date:  1985-04

Review 8.  Molecular basis of alpha-1-antitrypsin deficiency.

Authors:  M Brantly; T Nukiwa; R G Crystal
Journal:  Am J Med       Date:  1988-06-24       Impact factor: 4.965

9.  Alterations in relative proportions of microheterogenous forms of human alpha 1-acid glycoprotein in liver disease.

Authors:  N Serbource-Goguel Seta; G Durand; M Corbic; J Agneray; J Fegar
Journal:  J Hepatol       Date:  1986       Impact factor: 25.083

10.  Glycosylation of four acute-phase glycoproteins secreted by rat liver cells in vivo and in vitro. Effects of inflammation and dexamethasone.

Authors:  O Pos; W van Dijk; N Ladiges; C Linthorst; M Sala; D van Tiel; W Boers
Journal:  Eur J Cell Biol       Date:  1988-04       Impact factor: 4.492
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