Literature DB >> 22262179

Target of rapamcyin (TOR)-based therapeutics for cardiomyopathy: insights from zebrafish genetics.

Yonghe Ding, Xiaojing Sun, Margaret Redfield, Sudhir Kushwaha, Xiaolei Xu.   

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Year:  2012        PMID： 22262179      PMCID： PMC3315089          DOI： 10.4161/cc.11.3.19164

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


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  9 in total

1.  MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice.

Authors:  Denghong Zhang; Riccardo Contu; Michael V G Latronico; Jianlin Zhang; Jian Ling Zhang; Roberto Rizzi; Daniele Catalucci; Shigeki Miyamoto; Katherine Huang; Marcello Ceci; Yusu Gu; Nancy D Dalton; Kirk L Peterson; Kun-Liang Guan; Joan Heller Brown; Ju Chen; Nahum Sonenberg; Gianluigi Condorelli
Journal:  J Clin Invest       Date:  2010-07-19       Impact factor: 14.808

2.  Haploinsufficiency of target of rapamycin attenuates cardiomyopathies in adult zebrafish.

Authors:  Yonghe Ding; Xiaojing Sun; Wei Huang; Tiffany Hoage; Margaret Redfield; Sudhir Kushwaha; Sridhar Sivasubbu; Xueying Lin; Stephen Ekker; Xiaolei Xu
Journal:  Circ Res       Date:  2011-07-14       Impact factor: 17.367

3.  Rapamycin reverses hypertrophic cardiomyopathy in a mouse model of LEOPARD syndrome-associated PTPN11 mutation.

Authors:  Talita M Marin; Kimberly Keith; Benjamin Davies; David A Conner; Prajna Guha; Demetrios Kalaitzidis; Xue Wu; Jessica Lauriol; Bo Wang; Michael Bauer; Roderick Bronson; Kleber G Franchini; Benjamin G Neel; Maria I Kontaridis
Journal:  J Clin Invest       Date:  2011-02-21       Impact factor: 14.808

4.  Functions of the Wnt/β-catenin pathway in an anemia-induced zebrafish model of cardiomyopathy are location dependent.

Authors:  Tiffany Hoage; Xiaojing Sun; Xiaolei Xu
Journal:  Biochem Biophys Res Commun       Date:  2011-10-28       Impact factor: 3.575

5.  Rapamycin attenuates load-induced cardiac hypertrophy in mice.

Authors:  Tetsuo Shioi; Julie R McMullen; Oleg Tarnavski; Kimber Converso; Megan C Sherwood; Warren J Manning; Seigo Izumo
Journal:  Circulation       Date:  2003-03-17       Impact factor: 29.690

Review 6.  Autophagy in load-induced heart disease.

Authors:  Beverly A Rothermel; Joseph A Hill
Journal:  Circ Res       Date:  2008-12-05       Impact factor: 17.367

7.  Inhibition of mTOR signaling with rapamycin regresses established cardiac hypertrophy induced by pressure overload.

Authors:  Julie R McMullen; Megan C Sherwood; Oleg Tarnavski; Li Zhang; Adam L Dorfman; Tetsuo Shioi; Seigo Izumo
Journal:  Circulation       Date:  2004-06-07       Impact factor: 29.690

8.  Cardiac restricted overexpression of kinase-dead mammalian target of rapamycin (mTOR) mutant impairs the mTOR-mediated signaling and cardiac function.

Authors:  Wei-Hua Shen; Zhuang Chen; Shu Shi; Hanying Chen; Wuqiang Zhu; Anne Penner; Guixue Bu; Wei Li; David W Boyle; Michael Rubart; Loren J Field; Robert Abraham; Edward A Liechty; Weinian Shou
Journal:  J Biol Chem       Date:  2008-03-07       Impact factor: 5.157

9.  Cardiac hypertrophy involves both myocyte hypertrophy and hyperplasia in anemic zebrafish.

Authors:  Xiaojing Sun; Tiffany Hoage; Ping Bai; Yonghe Ding; Zhenyue Chen; Ruilin Zhang; Wei Huang; Ashad Jahangir; Barry Paw; Yi-Gang Li; Xiaolei Xu
Journal:  PLoS One       Date:  2009-08-12       Impact factor: 3.240
  9 in total
  4 in total

1.  Phenotyping an adult zebrafish lamp2 cardiomyopathy model identifies mTOR inhibition as a candidate therapy.

Authors:  Alexey V Dvornikov; Mingmin Wang; Jingchun Yang; Ping Zhu; Tai Le; Xueying Lin; Hung Cao; Xiaolei Xu
Journal:  J Mol Cell Cardiol       Date:  2019-06-20       Impact factor: 5.000

2.  BNIP3 is degraded by ULK1-dependent autophagy via MTORC1 and AMPK.

Authors:  Chang Wook Park; Sun Mi Hong; Eung-Sam Kim; Jung Hee Kwon; Kyong-Tai Kim; Hong Gil Nam; Kwan Yong Choi
Journal:  Autophagy       Date:  2013-01-04       Impact factor: 16.016

3.  The Molecular Mechanism of Glucagon-Like Peptide-1 Therapy in Alzheimer's Disease, Based on a Mechanistic Target of Rapamycin Pathway.

Authors:  Lin Li
Journal:  CNS Drugs       Date:  2017-07       Impact factor: 5.749

4.  A Langendorff-like system to quantify cardiac pump function in adult zebrafish.

Authors:  Hong Zhang; Alexey V Dvornikov; Inken G Huttner; Xiao Ma; Celine F Santiago; Diane Fatkin; Xiaolei Xu
Journal:  Dis Model Mech       Date:  2018-09-10       Impact factor: 5.758
  4 in total

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