Literature DB >> 22261739

The effect of orbital decompression surgery on refraction and intraocular pressure in patients with thyroid orbitopathy.

J H Norris1, J J Ross, M Kazim, D Selva, R Malhotra.   

Abstract

PURPOSE: To investigate the effect of orbital decompression surgery in thyroid orbitopathy (TO) on both refractive status and intraocular pressure (IOP). PATIENTS AND METHODS: A prospective, multicentre, consecutive audit of patients undergoing thyroid decompression surgery. Indications for surgery included cosmetically unacceptable proptosis or corneal exposure. Exclusion criteria included the following: previous orbital surgery, glaucoma, corneal disease, steroid use in the preceding 12 months, or an acute optic neuropathy. Automated refraction, keratometry, pachymetry, Hertel exophthalmometry, and IOP were recorded at 1 month pre- and 3 months postoperatively. IOP using the Tono-Pen (mean of three readings) was measured in the primary, upgaze, and downgaze positions.
RESULTS: Data were collected from 52 orbits of 33 patients (East Grinstead, New York, and Adelaide). There was no significant difference between pre- and postoperative data for sphere, cylinder, or central corneal thickness (CCT). The mean spherical equivalent was -0.43 ± 1.49 D pre-operatively and -0.28 ± 1.52 D postoperatively. The steepest meridian of corneal curvature was 93.1 degrees pre- and 94.2 degrees postoperatively, with no significant difference. Mean IOP significantly decreased when measuring by Goldmann applanation tonometry (GAT) (2.28 mm Hg, (*) P=0.001) and Tono-Pen (3.06 mm Hg, (*) P=<0.0001). IOP measured in upgaze was significantly greater than that in the primary position. Regression analysis between change in IOP and either Hertel exophthalmometry or the number of orbital walls decompressed was non-significant ((*)Student's t-test).
CONCLUSION: Patients with TO undergoing orbital decompression had, on average, with-the-rule astigmatism not affected by orbital decompression surgery. IOP was significantly reduced by decompression surgery although no relationship between IOP and the degree of decompression was observed.

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Year:  2012        PMID: 22261739      PMCID: PMC3325579          DOI: 10.1038/eye.2011.362

Source DB:  PubMed          Journal:  Eye (Lond)        ISSN: 0950-222X            Impact factor:   3.775


  38 in total

1.  Intraocular pressure changes after treatment for Graves' orbitopathy.

Authors:  H V Danesh-Meyer; P J Savino; V Deramo; R C Sergott; A F Smith
Journal:  Ophthalmology       Date:  2001-01       Impact factor: 12.079

2.  Orbital decompression: a comparison between trans-fornix/transcaruncular inferomedial and coronal inferomedial plus lateral approaches.

Authors:  Antonio Augusto V Cruz; Valmor Rios Leme
Journal:  Ophthalmic Plast Reconstr Surg       Date:  2003-11       Impact factor: 1.746

3.  Decrease in intraocular pressure after orbital decompression for thyroid orbitopathy.

Authors:  S Dev; K F Damji; C M DeBacker; T A Cox; J J Dutton; R R Allingham
Journal:  Can J Ophthalmol       Date:  1998-10       Impact factor: 1.882

4.  Retrobulbar pressures measured during surgical decompression of the orbit.

Authors:  A J Otto; L Koornneef; M P Mourits; L Deen-van Leeuwen
Journal:  Br J Ophthalmol       Date:  1996-12       Impact factor: 4.638

5.  Orbital decompression for thyroid orbitopathy.

Authors:  A A McNab
Journal:  Aust N Z J Ophthalmol       Date:  1997-02

6.  Intraocular pressure changes in normal subjects and the adhesive muscle syndrome.

Authors:  R J Zappia; J Z Winkelman; A J Gay
Journal:  Am J Ophthalmol       Date:  1971-04       Impact factor: 5.258

7.  Primary open angle glaucoma and hypothyroidism: chance or true association?

Authors:  J T Gillow; P Shah; E C O'Neill
Journal:  Eye (Lond)       Date:  1997       Impact factor: 3.775

8.  Is there an association between hypothyroidism and open-angle glaucoma in an elderly population? An epidemiologic study.

Authors:  Stephen P Motsko; Judith K Jones
Journal:  Ophthalmology       Date:  2008-03-20       Impact factor: 12.079

9.  Treatment of proptosis with fat removal orbital decompression in Graves' ophthalmopathy.

Authors:  J P Adenis; P Y Robert; J G Lasudry; Z Dalloul
Journal:  Eur J Ophthalmol       Date:  1998 Oct-Dec       Impact factor: 1.922

10.  Intraocular pressure and refractive changes following orbital decompression with intraconal fat excision.

Authors:  Suresh Sagili; Jean-Louis Desousa; Raman Malhotra
Journal:  Open Ophthalmol J       Date:  2008-04-16
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  8 in total

1.  Quantitative Assessment of Orbital Volume and Intraocular Pressure after Two-Wall Decompression in Thyroid Ophthalmopathy.

Authors:  Sang Min Park; Su Bong Nam; Jae Woo Lee; Kyeong Ho Song; Soo Jong Choi; Yong Chan Bae
Journal:  Arch Craniofac Surg       Date:  2015-08-11

Review 2.  Orbital decompression for thyroid eye disease: methods, outcomes, and complications.

Authors:  J M Jefferis; R K Jones; Z I Currie; J H Tan; S M Salvi
Journal:  Eye (Lond)       Date:  2017-12-15       Impact factor: 3.775

3.  Biometric and refractive changes after orbital decompression in Korean patients with thyroid-associated orbitopathy.

Authors:  W S Kim; Y S Chun; B Y Cho; J K Lee
Journal:  Eye (Lond)       Date:  2015-11-20       Impact factor: 3.775

4.  Blood-aqueous barrier integrity in patients with Graves' ophthalmopathy (GO), before and after rehabilitative surgery.

Authors:  A Kłysik; M Kozakiewicz
Journal:  Eye (Lond)       Date:  2015-02-13       Impact factor: 3.775

5.  Effect of Orbital Decompression on Corneal Topography in Patients with Thyroid Ophthalmopathy.

Authors:  Su Ah Kim; Su Kyung Jung; Ji Sun Paik; Suk-Woo Yang
Journal:  PLoS One       Date:  2015-09-09       Impact factor: 3.240

6.  The Clinical Features of Graves' Orbitopathy with Elevated Intraocular Pressure.

Authors:  Shu-Xian Fan; Peng Zeng; Zi-Jing Li; Jing Wang; Jia-Qi Liang; Yun-Ru Liao; Yu-Xin Hu; Ming-Tong Xu; Mei Wang
Journal:  J Ophthalmol       Date:  2021-01-25       Impact factor: 1.909

7.  Change of intraocular blood flow during treatment for thyroid eye disease.

Authors:  Masashi Mimura; Yuko Nishikawa; Keiko Inagaki; Yohei Sato; Yasushi Fujita; Don O Kikkawa
Journal:  Taiwan J Ophthalmol       Date:  2022-02-28

8.  Clinical factors affecting intraocular pressure change after orbital decompression surgery in thyroid-associated ophthalmopathy.

Authors:  Jae Hoon Jeong; Jeong Kyu Lee; Dong Ik Lee; Yeoun Sook Chun; Bo Youn Cho
Journal:  Clin Ophthalmol       Date:  2016-01-18
  8 in total

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