Literature DB >> 22260530

Diversity-oriented synthesis of polycyclic diazinic scaffolds.

Nicolas Gigant1, Elise Claveau, Pascal Bouyssou, Isabelle Gillaizeau.   

Abstract

An efficient and versatile synthesis of a polycyclic diazinic system starting from oxazine has been developed using a two-step Michael/retro Michael and cyclization sequence. The substrates were synthesized with good to high yields giving rapid access to molecular diversity.
© 2012 American Chemical Society

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Year:  2012        PMID: 22260530     DOI: 10.1021/ol203364b

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  2 in total

1.  Exploiting translational stalling peptides in an effort to extend azithromycin interaction within the prokaryotic ribosome nascent peptide exit tunnel.

Authors:  Arren Z Washington; Subhasish Tapadar; Alex George; Adegboyega K Oyelere
Journal:  Bioorg Med Chem       Date:  2015-05-06       Impact factor: 3.641

2.  Synthesis of Chromeno[3,4-b]piperazines by an Enol-Ugi/Reduction/Cyclization Sequence.

Authors:  Ana Bornadiego; Ana G Neo; Carlos F Marcos
Journal:  Molecules       Date:  2021-02-27       Impact factor: 4.411

  2 in total

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