BACKGROUND: Snake bite can cause acute kidney injury (AKI) through multiple mechanisms. Many of these patients have severe kidney injury requiring renal replacement therapy. The long-term outcome of survivors of such severe AKI is not known. METHODS: We prospectively followed up 60 patients who developed dialysis-requiring severe AKI following snake bite and had survived the hospital stay. RESULTS: A total of 25 (41%) patients showed persistent renal involvement in the form of renal dysfunction, proteinuria, or hypertension at a mean period of follow-up of 45 months. Totally 5% of the patients progressed to end-stage renal disease (ESRD) while 20% had glomerular filtration rate (GFR) <45 mL/min. CONCLUSIONS: Long-term outcome of snake bite and AKI is not benign with a significant percentage of patients continuing to have features of persistent renal damage.
BACKGROUND: Snake bite can cause acute kidney injury (AKI) through multiple mechanisms. Many of these patients have severe kidney injury requiring renal replacement therapy. The long-term outcome of survivors of such severe AKI is not known. METHODS: We prospectively followed up 60 patients who developed dialysis-requiring severe AKI following snake bite and had survived the hospital stay. RESULTS: A total of 25 (41%) patients showed persistent renal involvement in the form of renal dysfunction, proteinuria, or hypertension at a mean period of follow-up of 45 months. Totally 5% of the patients progressed to end-stage renal disease (ESRD) while 20% had glomerular filtration rate (GFR) <45 mL/min. CONCLUSIONS: Long-term outcome of snake bite and AKI is not benign with a significant percentage of patients continuing to have features of persistent renal damage.
Authors: Eliane Campos Alves; Jacqueline de Almeida Gonçalves Sachett; Vanderson Souza Sampaio; José Diego de Brito Sousa; Sâmella Silva de Oliveira; Elizandra Freitas do Nascimento; Alessandra Dos Santos Santos; Iran Mendonça da Silva; Ana Maria Moura da Silva; Fan Hui Wen; Mônica Colombini; Marcus Vinicius Guimarães de Lacerda; Wuelton Marcelo Monteiro; Luiz Carlos de Lima Ferreira Journal: PLoS One Date: 2018-08-17 Impact factor: 3.240
Authors: Challa Jaswanth; P S Priyamvada; Bobby Zachariah; Sathish Haridasan; Sreejith Parameswaran; R P Swaminathan Journal: Kidney Int Rep Date: 2019-01-28
Authors: Manuela B Pucca; Michelle V S Franco; Jilvando M Medeiros; Isadora S Oliveira; Shirin Ahmadi; Felipe A Cerni; Umberto Zottich; Bruna K Bassoli; Wuelton M Monteiro; Andreas H Laustsen Journal: J Venom Anim Toxins Incl Trop Dis Date: 2020-12-14