Min Li1, Ming-Hui Yang, Shao-Dan Li, Yi Liu. 1. Department of Traditional Chinese Medicine, General Hospital of Chinese PLA, Beijing 100853, China. kittenlee1115@126.com
Abstract
OBJECTIVE: To study the effects of Bushenhuoxue Granules on Parkinson's disease sleep scale (PDSS) score in Parkinson's patients. METHODS:120 patients were enrolled and divided into two groups randomly,the control group were treated with placebo and treatment group with Bushenhuoxue Granules, both group based on Madopar treatment. Double-blinded clinical trial was adopted in treatment period. Follow-up period for 6 months, PDSS was adopted to measure sleep condition of PD patients at baseline time, after 3 months and after 9 months. RESULTS:Bushenhuoxue Granules treatment group showed a higher efficacy than the placebo group in relieving the sleep disorders of Parkinson disease patients,both in treatment and follow-up period (P < 0.01). No adverse effects were found in this trial. CONCLUSIONS:Bushenhuoxue Granules can markedly improve sleep disorders in Parkinson's patients. The effects are stable and obvious along with the process of treatment.
RCT Entities:
OBJECTIVE: To study the effects of Bushenhuoxue Granules on Parkinson's disease sleep scale (PDSS) score in Parkinson'spatients. METHODS: 120 patients were enrolled and divided into two groups randomly,the control group were treated with placebo and treatment group with Bushenhuoxue Granules, both group based on Madopar treatment. Double-blinded clinical trial was adopted in treatment period. Follow-up period for 6 months, PDSS was adopted to measure sleep condition of PDpatients at baseline time, after 3 months and after 9 months. RESULTS: Bushenhuoxue Granules treatment group showed a higher efficacy than the placebo group in relieving the sleep disorders of Parkinson diseasepatients,both in treatment and follow-up period (P < 0.01). No adverse effects were found in this trial. CONCLUSIONS: Bushenhuoxue Granules can markedly improve sleep disorders in Parkinson'spatients. The effects are stable and obvious along with the process of treatment.