Literature DB >> 22257213

Discovery and development of spleen tyrosine kinase (SYK) inhibitors.

Rajinder Singh1, Esteban S Masuda, Donald G Payan.   

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Year:  2012        PMID: 22257213     DOI: 10.1021/jm201271b

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


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  19 in total

Review 1.  Progress in Small Molecule Therapeutics for the Treatment of Retinoblastoma.

Authors:  Eleanor M Pritchard; Michael A Dyer; R Kiplin Guy
Journal:  Mini Rev Med Chem       Date:  2016       Impact factor: 3.862

2.  Pharmacological Inhibition of Spleen Tyrosine Kinase Suppressed Neuroinflammation and Cognitive Dysfunction in LPS-Induced Neurodegeneration Model.

Authors:  Min Woo Kim; Kyonghwan Choe; Jun Sung Park; Hyeon Jin Lee; Min Hwa Kang; Riaz Ahmad; Myeong Ok Kim
Journal:  Cells       Date:  2022-05-28       Impact factor: 7.666

3.  Pharmacokinetics and efficacy of the spleen tyrosine kinase inhibitor r406 after ocular delivery for retinoblastoma.

Authors:  Eleanor M Pritchard; Elizabeth Stewart; Fangyi Zhu; Cori Bradley; Lyra Griffiths; Lei Yang; Praveen Kumar Suryadevara; Jiakun Zhang; Burgess B Freeman; R Kiplin Guy; Michael A Dyer
Journal:  Pharm Res       Date:  2014-06-07       Impact factor: 4.200

4.  A combined experimental and computational study of Vam3, a derivative of resveratrol, and Syk interaction.

Authors:  Ming Jiang; Renping Liu; Ying Chen; Qisheng Zheng; Saijun Fan; Peixun Liu
Journal:  Int J Mol Sci       Date:  2014-09-25       Impact factor: 5.923

5.  In vitro pharmacological profiling of R406 identifies molecular targets underlying the clinical effects of fostamatinib.

Authors:  Michael G Rolf; Jon O Curwen; Margaret Veldman-Jones; Cath Eberlein; Jianyan Wang; Alex Harmer; Caroline J Hellawell; Martin Braddock
Journal:  Pharmacol Res Perspect       Date:  2015-09-04

6.  A Novel Triazolopyridine-Based Spleen Tyrosine Kinase Inhibitor That Arrests Joint Inflammation.

Authors:  Gregory D Ferguson; Mercedes Delgado; Veronique Plantevin-Krenitsky; Kristen Jensen-Pergakes; R J Bates; Sanaa Torres; Maria Celeridad; Heather Brown; Kelven Burnett; Lisa Nadolny; Lida Tehrani; Garrick Packard; Barbra Pagarigan; Jason Haelewyn; Trish Nguyen; Li Xu; Yang Tang; Matthew Hickman; Frans Baculi; Steven Pierce; Keiji Miyazawa; Pilgrim Jackson; Philip Chamberlain; Laurie LeBrun; Weilin Xie; Brydon Bennett; Kate Blease
Journal:  PLoS One       Date:  2016-01-12       Impact factor: 3.240

Review 7.  Syk inhibitors in clinical development for hematological malignancies.

Authors:  Delong Liu; Aleksandra Mamorska-Dyga
Journal:  J Hematol Oncol       Date:  2017-07-28       Impact factor: 17.388

Review 8.  Syk Activity Is Dispensable for Platelet GP1b-IX-V Signaling.

Authors:  Rachit Badolia; John C Kostyak; Carol Dangelmaier; Satya P Kunapuli
Journal:  Int J Mol Sci       Date:  2017-06-09       Impact factor: 5.923

9.  Novel Agents and Emerging Strategies for Targeting the B-Cell Receptor Pathway in CLL.

Authors:  Dimitar G Efremov; Adrian Wiestner; Luca Laurenti
Journal:  Mediterr J Hematol Infect Dis       Date:  2012-10-09       Impact factor: 2.576

10.  Crystal Structures of Spleen Tyrosine Kinase in Complex with Two Novel 4-Aminopyrido[4,3-d] Pyrimidine Derivative Inhibitors.

Authors:  Sang Jae Lee; Jang-Sik Choi; Seoung Min Bong; Hae-Jun Hwang; Jaesang Lee; Ho-Juhn Song; Jaekyoo Lee; Jung-Ho Kim; Jong Sung Koh; Byung Il Lee
Journal:  Mol Cells       Date:  2018-06-12       Impact factor: 5.034

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