Development of an interactive Coronary Doppler Vibrometry system for detection of coronary artery disease.

Coronary artery disease is a deadly and costly condition and represents an important public health issue globally. Coronary Doppler vibrometry (CDV), a new noninvasive coronary artery stenosis detection technique, showed encouraging results in our recent clinical study. However, the CDV system required lengthy offline data analysis, thus it did not provide any feedback during examination on the quality of data, not to mention analysis results. To overcome these limitations, we have developed a new CDV system that interactively performs acquisition, analysis and display of a complete data set while a subject is still on the examination table. Our system is based on a commercial ultrasound machine, and it will be a useful tool for CDV research and clinical studies in the future.