Literature DB >> 22255099

Chronic stimulation of the semicircular canals using a multichannel vestibular prosthesis: effects on locomotion and angular vestibulo-ocular reflex in chinchillas.

Daniel Q Sun1, Mehdi A Rahman, Gene Fridman, Chenkai Dai, Bryce Chiang, Charles C Della Santina.   

Abstract

Bilateral loss of vestibular sensation causes difficulty maintaining stable vision, posture and gait. An implantable prosthesis that partly restores vestibular sensation could significantly improve quality of life for individuals disabled by this disorder. We have developed a head-mounted multichannel vestibular prosthesis (MVP) that restores sufficient semicircular canal function to recreate a 3D angular vestibulo-ocular reflex (aVOR). In this study, we evaluated effects of chronic MVP stimulation on locomotion in chinchillas. Two of three animals examined exhibited significant improvements in both locomotion and aVOR.

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Mesh：

Year:  2011        PMID： 22255099      PMCID： PMC3307049          DOI： 10.1109/IEMBS.2011.6090584

Source DB:  PubMed          Journal:  Conf Proc IEEE Eng Med Biol Soc        ISSN： 1557-170X


  22 in total

1.  Prototype neural semicircular canal prosthesis using patterned electrical stimulation.

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Journal:  Ann Biomed Eng       Date:  2000-05       Impact factor: 3.934

2.  Postural and locomotor control in normal and vestibularly deficient mice.

Authors:  P-P Vidal; L Degallaix; P Josset; J-P Gasc; K E Cullen
Journal:  J Physiol       Date:  2004-07-08       Impact factor: 5.182

3.  Inexpensive system for real-time 3-dimensional video-oculography using a fluorescent marker array.

Authors:  Americo A Migliaccio; Hamish G Macdougall; Lloyd B Minor; Charles C Della Santina
Journal:  J Neurosci Methods       Date:  2004-11-28       Impact factor: 2.390

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Journal:  Acta Otolaryngol       Date:  1969-10       Impact factor: 1.494

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Authors:  E Fluur; A Mellström
Journal:  Laryngoscope       Date:  1970-11       Impact factor: 3.325

6.  Auditory and vestibular defects in the circling (ci2) rat mutant.

Authors:  A Kaiser; M Fedrowitz; U Ebert; E Zimmermann; H J Hedrich; D Wedekind; W Löscher
Journal:  Eur J Neurosci       Date:  2001-10       Impact factor: 3.386

7.  Circling behavior produced by unilateral lesions of the central vestibular system.

Authors:  F Shima; R Hassler
Journal:  Appl Neurophysiol       Date:  1982

8.  Eye movements in patients with superior canal dehiscence syndrome align with the abnormal canal.

Authors:  P D Cremer; L B Minor; J P Carey; C C Della Santina
Journal:  Neurology       Date:  2000-12-26       Impact factor: 9.910

9.  Effects of intratympanic gentamicin on vestibular afferents and hair cells in the chinchilla.

Authors:  Timo P Hirvonen; Lloyd B Minor; Timothy E Hullar; John P Carey
Journal:  J Neurophysiol       Date:  2004-09-29       Impact factor: 2.714

10.  System design and performance of a unilateral horizontal semicircular canal prosthesis.

Authors:  Wangsong Gong; Daniel M Merfeld
Journal:  IEEE Trans Biomed Eng       Date:  2002-02       Impact factor: 4.538
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  9 in total

1.  A CMOS Neural Interface for a Multichannel Vestibular Prosthesis.

Authors:  Kristin N Hageman; Zaven K Kalayjian; Francisco Tejada; Bryce Chiang; Mehdi A Rahman; Gene Y Fridman; Chenkai Dai; Philippe O Pouliquen; Julio Georgiou; Charles C Della Santina; Andreas G Andreou
Journal:  IEEE Trans Biomed Circuits Syst       Date:  2015-05-11       Impact factor: 3.833

2.  Vestibular implantation and longitudinal electrical stimulation of the semicircular canal afferents in human subjects.

Authors:  James O Phillips; Leo Ling; Kaibao Nie; Elyse Jameyson; Christopher M Phillips; Amy L Nowack; Justin S Golub; Jay T Rubinstein
Journal:  J Neurophysiol       Date:  2015-02-04       Impact factor: 2.714

3.  Safe direct current stimulation to expand capabilities of neural prostheses.

Authors:  Gene Y Fridman; Charles C Della Santina
Journal:  IEEE Trans Neural Syst Rehabil Eng       Date:  2013-03       Impact factor: 3.802

Review 4.  Progress toward development of a multichannel vestibular prosthesis for treatment of bilateral vestibular deficiency.

Authors:  Gene Y Fridman; Charles C Della Santina
Journal:  Anat Rec (Hoboken)       Date:  2012-10-08       Impact factor: 2.064

5.  Multichannel vestibular prosthesis employing modulation of pulse rate and current with alignment precompensation elicits improved VOR performance in monkeys.

Authors:  Natan S Davidovics; Mehdi A Rahman; Chenkai Dai; JoongHo Ahn; Gene Y Fridman; Charles C Della Santina
Journal:  J Assoc Res Otolaryngol       Date:  2013-01-26

6.  Postural responses to electrical stimulation of the vestibular end organs in human subjects.

Authors:  Christopher Phillips; Christina Defrancisci; Leo Ling; Kaibao Nie; Amy Nowack; James O Phillips; Jay T Rubinstein
Journal:  Exp Brain Res       Date:  2013-06-15       Impact factor: 1.972

7.  Longitudinal performance of an implantable vestibular prosthesis.

Authors:  Christopher Phillips; Leo Ling; Trey Oxford; Amy Nowack; Kaibao Nie; Jay T Rubinstein; James O Phillips
Journal:  Hear Res       Date:  2014-09-22       Impact factor: 3.208

8.  Development of a multichannel vestibular prosthesis prototype by modification of a commercially available cochlear implant.

Authors:  Nicolas S Valentin; Kristin N Hageman; Chenkai Dai; Charles C Della Santina; Gene Y Fridman
Journal:  IEEE Trans Neural Syst Rehabil Eng       Date:  2013-05-01       Impact factor: 3.802

9.  The Dynamics of Prosthetically Elicited Vestibulo-Ocular Reflex Function Across Frequency and Context in the Rhesus Monkey.

Authors:  James O Phillips; Leo Ling; Amy L Nowack; Christopher M Phillips; Kaibao Nie; Jay T Rubinstein
Journal:  Front Neurosci       Date:  2018-05-15       Impact factor: 4.677
  9 in total

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