Literature DB >> 22254830

Robustness of inverse perturbation for discrete event control.

Nidhal Bouaynaya1, Roman Shterenberg, Dan Schonfeld.   

Abstract

We study the robustness of the inverse perturbation solution in discrete-time systems modeled by homogeneous Markov chains. We cast the optimal inverse perturbation control as a strictly convex optimization problem, which admits a unique global solution. We show that the optimal inverse perturbation control is robust to estimation errors in the original network. The derived results are applied to the Human melanoma gene regulatory network, where the aim is to force the network to converge to a desired steady-state distribution of gene regulation.

Entities:  

Mesh:

Substances:

Year:  2011        PMID: 22254830      PMCID: PMC3495572          DOI: 10.1109/IEMBS.2011.6090674

Source DB:  PubMed          Journal:  Conf Proc IEEE Eng Med Biol Soc        ISSN: 1557-170X


  1 in total

1.  Inverse perturbation for optimal intervention in gene regulatory networks.

Authors:  Nidhal Bouaynaya; Roman Shterenberg; Dan Schonfeld
Journal:  Bioinformatics       Date:  2010-11-08       Impact factor: 6.937

  1 in total
  1 in total

1.  Methods for Optimal Intervention in Gene Regulatory Networks.

Authors:  Nidhal Bouaynaya; Roman Shterenberg; Dan Schonfeld
Journal:  IEEE Signal Process Mag       Date:  2012       Impact factor: 12.551

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.