AIM: To investigate the effect of alcohol on the metabolic syndrome (MS) and fatty liver in Japanese men and women. METHODS: A cross-sectional study was conducted in a medical health checkup program at a general hospital. This study involved 18 571 Japanese men and women, 18-88 years of age, with a mean body mass index of 22.6 kg/m(2). A standardized questionnaire was administered. The total amount of alcohol consumed per week was calculated, and categorized into four grades. Fatty liver was examined by ultrasound modified criteria of the revised National Cholesterol Education Program Adult Treatment Panel III and the new International Diabetes Federation. RESULTS: The prevalence of fatty liver decreased in men and women with light to moderate alcohol consumption, whereas the prevalence of MS was not so changed. The prevalence of fatty liver of any grade in men was lower than that in those with no or minimal alcohol consumption. In women with light to moderate alcohol consumption, prevalence of fatty liver was lower than that in women with no or minimal alcohol consumption. By logistic regression analysis, the odds ratio (OR) for MS in women with light alcohol consumption was decreased to < 1.0, but this change was not clear in men. The OR for fatty liver was clearly < 1.0 in men with any level of alcohol consumption and in women with light to moderate consumption. CONCLUSION: Light to moderate alcohol consumption has a favorable effect for fatty liver, but not for MS in Japanese men and women.
AIM: To investigate the effect of alcohol on the metabolic syndrome (MS) and fatty liver in Japanese men and women. METHODS: A cross-sectional study was conducted in a medical health checkup program at a general hospital. This study involved 18 571 Japanese men and women, 18-88 years of age, with a mean body mass index of 22.6 kg/m(2). A standardized questionnaire was administered. The total amount of alcohol consumed per week was calculated, and categorized into four grades. Fatty liver was examined by ultrasound modified criteria of the revised National Cholesterol Education Program Adult Treatment Panel III and the new International Diabetes Federation. RESULTS: The prevalence of fatty liver decreased in men and women with light to moderate alcohol consumption, whereas the prevalence of MS was not so changed. The prevalence of fatty liver of any grade in men was lower than that in those with no or minimal alcohol consumption. In women with light to moderate alcohol consumption, prevalence of fatty liver was lower than that in women with no or minimal alcohol consumption. By logistic regression analysis, the odds ratio (OR) for MS in women with light alcohol consumption was decreased to < 1.0, but this change was not clear in men. The OR for fatty liver was clearly < 1.0 in men with any level of alcohol consumption and in women with light to moderate consumption. CONCLUSION: Light to moderate alcohol consumption has a favorable effect for fatty liver, but not for MS in Japanese men and women.
Authors: Hae Jin Kim; Hyeong Jin Kim; Kwang Eun Lee; Dae Jung Kim; Soo Kyung Kim; Chul Woo Ahn; Sung-Kil Lim; Kyung Rae Kim; Hyun Chul Lee; Kap Bum Huh; Bong Soo Cha Journal: Arch Intern Med Date: 2004-10-25
Authors: C S Fuchs; M J Stampfer; G A Colditz; E L Giovannucci; J E Manson; I Kawachi; D J Hunter; S E Hankinson; C H Hennekens; B Rosner Journal: N Engl J Med Date: 1995-05-11 Impact factor: 91.245
Authors: Soner Akbaba; Hüseyin Köseoğlu; Bahadır Osman Bozkırlı; Fatma Ebru Akın; Rıza Haldun Gündoğdu; Osman Ersoy; Jale Karakaya; Pamir Eren Ersoy Journal: Int J Clin Exp Med Date: 2014-05-15
Authors: Eun Young Park; Min Kyung Lim; Jin-Kyoung Oh; Heeyoun Cho; Mi Jin Bae; E Hwa Yun; Dong-il Kim; Hai-Rim Shin Journal: PLoS One Date: 2013-05-07 Impact factor: 3.240