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Literature DB >> 22252815

Klebsiella pneumoniae ST258 producing KPC-3 identified in italy carries novel plasmids and OmpK36/OmpK35 porin variants.

Aurora García-Fernández¹, Laura Villa, Claudio Carta, Carolina Venditti, Alessandra Giordano, Mario Venditti, Carlo Mancini, Alessandra Carattoli.

Abstract

A carbapenemase-resistant Klebsiella pneumoniae strain, clone ST258 producing KPC-3, was fully characterized. The entire plasmid content was investigated, thereby identifying plasmids of the IncFII(k) (two of them similar to pKPQIL and pKPN3, respectively), IncX, and ColE types, carrying a formidable set of resistance genes against toxic compounds, metals, and antimicrobial drugs and a novel iron(III) uptake system.

Entities: Chemical Gene Species

Mesh：

Substances：

Year: 2012 PMID： 22252815 PMCID： PMC3318348 DOI： 10.1128/AAC.05308-11

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

22 in total

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5. Outbreak of KPC-3-producing, and colistin-resistant, Klebsiella pneumoniae infections in two Sicilian hospitals.

Authors: M L Mezzatesta; F Gona; C Caio; V Petrolito; D Sciortino; A Sciacca; C Santangelo; S Stefani
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6. High-level carbapenem resistance in a Klebsiella pneumoniae clinical isolate is due to the combination of bla(ACT-1) beta-lactamase production, porin OmpK35/36 insertional inactivation, and down-regulation of the phosphate transport porin phoe.

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7. Arrival of Klebsiella pneumoniae producing KPC carbapenemase in the United Kingdom.

Authors: Neil Woodford; Jiancheng Zhang; Marina Warner; Mary E Kaufmann; Jorge Matos; Alan Macdonald; Daniel Brudney; David Sompolinsky; Shiri Navon-Venezia; David M Livermore
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8. Detection of the Klebsiella pneumoniae carbapenemase type 2 Carbapenem-hydrolyzing enzyme in clinical isolates of Citrobacter freundii and K. oxytoca carrying a common plasmid.

Authors: J Kamile Rasheed; James W Biddle; Karen F Anderson; Laraine Washer; Carol Chenoweth; John Perrin; Duane W Newton; Jean B Patel
Journal: J Clin Microbiol Date: 2008-04-02 Impact factor: 5.948

9. Emergence of clonally related Klebsiella pneumoniae isolates of sequence type 258 producing plasmid-mediated KPC carbapenemase in Norway and Sweden.

Authors: Ørjan Samuelsen; Umaer Naseer; Ståle Tofteland; Dag Harald Skutlaberg; Annette Onken; Reidar Hjetland; Arnfinn Sundsfjord; Christian G Giske
Journal: J Antimicrob Chemother Date: 2009-02-13 Impact factor: 5.790

10. Molecular detection of GES-2 extended spectrum Beta-lactamase producing Pseudomonas aeruginosa in Pretoria, South Africa.

Authors: Gerhard F Weldhagen; Andrea Prinsloo
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86 in total

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Journal: Antimicrob Agents Chemother Date: 2015-09-21 Impact factor: 5.191

2. Molecular Characterization of an Atypical IncX3 Plasmid pKPC-NY79 Carrying bla KPC-2 in a Klebsiella pneumoniae.

Authors: Pak-Leung Ho; Yuk-Yam Cheung; Wai-U Lo; Zhen Li; Kin-Hung Chow; Chi-Ho Lin; Jasper Fuk-Woo Chan; Vincent Chi-Chung Cheng
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3. Complete nucleotide sequence of a blaKPC-harboring IncI2 plasmid and its dissemination in New Jersey and New York hospitals.

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4. Predictability of Phenotype in Relation to Common β-Lactam Resistance Mechanisms in Escherichia coli and Klebsiella pneumoniae.

Authors: Alex Agyekum; Alicia Fajardo-Lubián; Xiaoman Ai; Andrew N Ginn; Zhiyong Zong; Xuejun Guo; John Turnidge; Sally R Partridge; Jonathan R Iredell
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5. A rapid matrix-assisted laser desorption ionization-time of flight mass spectrometry-based method for single-plasmid tracking in an outbreak of carbapenem-resistant Enterobacteriaceae.

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6. Resistance to Ceftazidime-Avibactam Is Due to Transposition of KPC in a Porin-Deficient Strain of Klebsiella pneumoniae with Increased Efflux Activity.

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7. Surveillance and characterization of carbapenemase-producing Klebsiella pneumoniae recovered from patient stool samples at a tertiary care medical center.

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