Literature DB >> 22251960

Neurodegenerative disease: Preventing 'SIRTain' death by mutant huntingtin.

Monica Hoyos Flight.   

Abstract

Entities:  

Year:  2012        PMID： 22251960     DOI： 10.1038/nrn3182

Source DB:  PubMed          Journal:  Nat Rev Neurosci        ISSN： 1471-003X            Impact factor:   34.870


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  2 in total

1.  Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets.

Authors:  Mali Jiang; Jiawei Wang; Jinrong Fu; Lin Du; Hyunkyung Jeong; Tim West; Lan Xiang; Qi Peng; Zhipeng Hou; Huan Cai; Tamara Seredenina; Nicolas Arbez; Shanshan Zhu; Katherine Sommers; Jennifer Qian; Jiangyang Zhang; Susumu Mori; X William Yang; Kellie L K Tamashiro; Susan Aja; Timothy H Moran; Ruth Luthi-Carter; Bronwen Martin; Stuart Maudsley; Mark P Mattson; Robert H Cichewicz; Christopher A Ross; David M Holtzman; Dimitri Krainc; Wenzhen Duan
Journal:  Nat Med       Date:  2011-12-18       Impact factor: 53.440

2.  Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway.

Authors:  Hyunkyung Jeong; Dena E Cohen; Libin Cui; Andrea Supinski; Jeffrey N Savas; Joseph R Mazzulli; John R Yates; Laura Bordone; Leonard Guarente; Dimitri Krainc
Journal:  Nat Med       Date:  2011-12-18       Impact factor: 53.440
  2 in total

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