Literature DB >> 22249238

Clinical trials for glaucoma neuroprotection are not impossible.

Harry A Quigley1.   

Abstract

PURPOSE OF REVIEW: To discuss issues that affect development of new glaucoma treatments known as neuroprotection. RECENT
FINDINGS: There are barriers to neuroprotection trials for glaucoma.
SUMMARY: With design features discussed in the review, neuroprotection trials can be effectively carried out.

Entities:  

Mesh：

Substances：

Year:  2012        PMID： 22249238     DOI： 10.1097/ICU.0b013e32834ff490

Source DB:  PubMed          Journal:  Curr Opin Ophthalmol        ISSN： 1040-8738            Impact factor:   3.761


  19 in total

1.  Evaluation of Visual Field and Imaging Outcomes for Glaucoma Clinical Trials (An American Ophthalomological Society Thesis).

Authors:  David F Garway-Heath; Ana Quartilho; Philip Prah; David P Crabb; Qian Cheng; Haogang Zhu
Journal:  Trans Am Ophthalmol Soc       Date:  2017-08-22

2.  Improving the Feasibility of Glaucoma Clinical Trials Using Trend-Based Visual Field Progression Endpoints.

Authors:  Zhichao Wu; David P Crabb; Balwantray C Chauhan; Jonathan G Crowston; Felipe A Medeiros
Journal:  Ophthalmol Glaucoma       Date:  2019-01-17

Review 3.  Pharmacotherapy of glaucoma.

Authors:  Doreen Schmidl; Leopold Schmetterer; Gerhard Garhöfer; Alina Popa-Cherecheanu
Journal:  J Ocul Pharmacol Ther       Date:  2015-01-14       Impact factor: 2.671

Review 4.  Detection and measurement of clinically meaningful visual field progression in clinical trials for glaucoma.

Authors:  C Gustavo De Moraes; Jeffrey M Liebmann; Leonard A Levin
Journal:  Prog Retin Eye Res       Date:  2016-10-20       Impact factor: 21.198

Review 5.  Axon injury signaling and compartmentalized injury response in glaucoma.

Authors:  Stephanie B Syc-Mazurek; Richard T Libby
Journal:  Prog Retin Eye Res       Date:  2019-07-10       Impact factor: 21.198

Review 6.  Neuroprotection for treatment of glaucoma in adults.

Authors:  Dayse F Sena; Kristina Lindsley
Journal:  Cochrane Database Syst Rev       Date:  2017-01-25

Review 7.  Neuroprotection for treatment of glaucoma in adults.

Authors:  Dayse F Sena; Kristina Lindsley
Journal:  Cochrane Database Syst Rev       Date:  2013-02-28

Review 8.  Solving the lost in translation problem: improving the effectiveness of translational research.

Authors:  Ceren Ergorul; Leonard A Levin
Journal:  Curr Opin Pharmacol       Date:  2012-09-11       Impact factor: 5.547

Review 9.  Stem cells, retinal ganglion cells and glaucoma.

Authors:  Valentin M Sluch; Donald J Zack
Journal:  Dev Ophthalmol       Date:  2014-04-10

Review 10.  From mechanosensitivity to inflammatory responses: new players in the pathology of glaucoma.

Authors:  David Križaj; Daniel A Ryskamp; Ning Tian; Gülgün Tezel; Claire H Mitchell; Vladlen Z Slepak; Valery I Shestopalov
Journal:  Curr Eye Res       Date:  2013-10-21       Impact factor: 2.424
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