O Amira1. 1. Department of Medicine, College of Medicine, University of Lagos, Idi-Araba, Lagos. toyinamira@yahoo.com
Abstract
OBJECTIVE: Depression is the most common psychiatric illness in patients with chronic kidney disease (CKD). Depression has been shown to affect mortality in end-stage renal disease patients. The objective of this study was to determine prevalence of depressive symptoms among CKD patients. MATERIALS AND METHODS: A cross-sectional study of patients with CKD (Stages 3-5) attending the renal clinic of a tertiary hospital was conducted. Demographic and clinical data were documented. A self-administered Zung depression questionnaire was administered. The Zung depression questionnaire has 20 weighted questions. Individuals with a total score of 50 are considered to be depressed, while a score of 70 and above is indicative of severe depression. RESULTS: One hundred and eighteen patients and fifty controls were interviewed. There were 73 (61.9%) males and 45 (38.1%) female patients. The mean age did not differ: males 43.8 ± 15.4 years, females 43.2 ± 14.7 yrs, P = 0.83. The prevalence of depression among the CKD patients was 23.7%, while for the control group was 2%; χ2 = 10.14, P < 0.001. Further analysis showed that CKD patients on dialysis were more likely to be depressed than the pre-dialysis patients with frequency of depressive symptoms of 34.5% for dialysis patients versus 13.3% in pre-dialysis patients; χ2 = 6.17, P = 0.01. No difference was observed in the mean Zung score among males, and female patients mean Zung score was 40.1 in females and 40.7 in male patients; P > 0.05. CONCLUSION: Depression is highly prevalent among our patients with CKD and treatment modality was the major predictor of depression among our patients.
OBJECTIVE:Depression is the most common psychiatric illness in patients with chronic kidney disease (CKD). Depression has been shown to affect mortality in end-stage renal diseasepatients. The objective of this study was to determine prevalence of depressive symptoms among CKDpatients. MATERIALS AND METHODS: A cross-sectional study of patients with CKD (Stages 3-5) attending the renal clinic of a tertiary hospital was conducted. Demographic and clinical data were documented. A self-administered Zung depression questionnaire was administered. The Zung depression questionnaire has 20 weighted questions. Individuals with a total score of 50 are considered to be depressed, while a score of 70 and above is indicative of severe depression. RESULTS: One hundred and eighteen patients and fifty controls were interviewed. There were 73 (61.9%) males and 45 (38.1%) female patients. The mean age did not differ: males 43.8 ± 15.4 years, females 43.2 ± 14.7 yrs, P = 0.83. The prevalence of depression among the CKDpatients was 23.7%, while for the control group was 2%; χ2 = 10.14, P < 0.001. Further analysis showed that CKDpatients on dialysis were more likely to be depressed than the pre-dialysis patients with frequency of depressive symptoms of 34.5% for dialysis patients versus 13.3% in pre-dialysis patients; χ2 = 6.17, P = 0.01. No difference was observed in the mean Zung score among males, and female patients mean Zung score was 40.1 in females and 40.7 in male patients; P > 0.05. CONCLUSION:Depression is highly prevalent among our patients with CKD and treatment modality was the major predictor of depression among our patients.
Authors: Vincent J Ganu; Vincent Boima; David N Adjei; Joana S Yendork; Ida D Dey; Ernest Yorke; Charles C Mate-Kole; Michael O Mate-Kole Journal: Ghana Med J Date: 2018-03
Authors: Glen James; Elisabeth Nyman; Marcy Fitz-Randolph; Anna Niklasson; Katarina Hedman; Jonatan Hedberg; Eric T Wittbrodt; Jennie Medin; Carol Moreno Quinn; Alaster M Allum; Cathy Emmas Journal: J Med Internet Res Date: 2020-07-15 Impact factor: 5.428